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Andrew G. Nicholson
Researcher at National Institutes of Health
Publications - 512
Citations - 87875
Andrew G. Nicholson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Lung cancer & Idiopathic pulmonary fibrosis. The author has an hindex of 113, co-authored 477 publications receiving 73860 citations. Previous affiliations of Andrew G. Nicholson include National Yang-Ming University & University College London.
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Journal ArticleDOI
Paradigm shifts in lung cancer as defined in the new IASLC/ATS/ERS lung adenocarcinoma classification
William D. Travis,Elisabeth Brambilla,P. Van Schil,G.V. Scagliotti,Rudolf M. Huber,J-P Sculier,Johan Vansteenkiste,Andrew G. Nicholson +7 more
TL;DR: A series of major paradigm shifts are outlined in this classification that will result in major changes in the approach to diagnosis of lung cancer compared to those outlined in previous World Health Organization (WHO) classifications.
Journal ArticleDOI
ALK translocation is associated with ALK immunoreactivity and extensive signet-ring morphology in primary lung adenocarcinoma.
Sanjay Popat,David Gonzalez,Toon Min,John Swansbury,Melissa Dainton,James Croud,Alexandra Rice,Andrew G. Nicholson +7 more
TL;DR: ALK rearrangement is strongly associated with ALK immunoreactivity, and was seen only in tumours with pure signet-ring morphology and solid growth pattern, with TTF-1 positivity aiding in proving primary pulmonary origin.
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Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease
TL;DR: This study identifies a specific macrophages phenotype in the lungs of patients with COPD who are glucocorticosteroid insensitive with a density of 1.036 to 1.048 g/mL but do not correspond to the current concept of macrophage phenotypes.
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Full thickness eosinophilia in oesophageal leiomyomatosis and idiopathic eosinophilic oesophagitis. A common allergic inflammatory profile
TL;DR: Oesophageal leiomyomatosis and idiopathic eosinophilic oesophagitis are both extremely rare and the possibility that there is a common underlying allergic component to both disorders is raised.
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A comprehensive diagnostic approach using galactomannan, targeted β-d-glucan, baseline computerized tomography and biopsy yields a significant burden of invasive fungal disease in at risk haematology patients
M. Mansour Ceesay,Sujal R. Desai,Lisa Berry,Joanne Cleverley,Christopher C. Kibbler,Sabine Pomplun,Andrew G. Nicholson,Abdel Douiri,Jim Wade,Melvyn Smith,Ghulam J. Mufti,Antonio Pagliuca +11 more
TL;DR: A combined diagnostic approach identified a high incidence of IFD and important risk factors in this cohort of patients and detected all biopsy‐proven mould IFD.