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Andrew G. Nicholson
Researcher at National Institutes of Health
Publications - 512
Citations - 87875
Andrew G. Nicholson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Lung cancer & Idiopathic pulmonary fibrosis. The author has an hindex of 113, co-authored 477 publications receiving 73860 citations. Previous affiliations of Andrew G. Nicholson include National Yang-Ming University & University College London.
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Journal ArticleDOI
Utility of Nuclear Grading System in Epithelioid Malignant Pleural Mesothelioma in Biopsy-heavy Setting: An External Validation Study of 563 Cases.
Yu Zhi Zhang,C. Brambilla,Philip L. Molyneaux,Alexandra Rice,Jan Lukas Robertus,Simon Jordan,Eric Lim,Loic Lang-Lazdunski,S Begum,Michael Dusmet,Vladimir Anikin,Emma Beddow,Jonathan Finch,Nizar Asadi,Sanjay Popat,Sanjay Popat,William O.C.M. Cookson,Miriam F. Moffatt,Andrew G. Nicholson +18 more
TL;DR: The utility of nuclear grade in epithelioid MPM using a biopsy-heavy cohort provided the tissue sample met minimum dimensional criteria was confirmed and suggested sampling 3 sites or a maximum tissue dimension of at least 20 mm from a single site is optimal for nuclear grade assessment.
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A rare case of squamous cell carcinoma of the lung harbouring ALK and BRAF activating mutations.
Doraid Alrifai,Sanjay Popat,Sanjay Popat,Merina Ahmed,David Gonzalez,Andrew G. Nicholson,John du Parcq,Tim Benepal +7 more
TL;DR: This case represents a late gentleman with squamous cell carcinoma of the lung with both a BRAF mutation and ALK rearrangement prior to treatment.
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Diffuse alveolar haemorrhage associated with subsequent development of ANCA positivity and emphysema in three young adults
Anna Stainer,Alex Rice,Anand Devaraj,Joseph Barnett,Jacqueline Donovan,Maria Kokosi,Andrew G. Nicholson,Tom Cairns,Athol U. Wells,Elisabetta A. Renzoni +9 more
TL;DR: Three cases presenting with recurrent pulmonary haemorrhage who, several years after first presentation, develop anti myeloperoxidase antibodies (MPO) positivity, emphysema on CT and, in one case, renal involvement, highlight a possible role played by autoimmune phenomena, even when DAH is initially diagnosed as “idiopathic”.
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Mixed ventilatory defects in pulmonary sarcoidosis: prevalence and clinical features.
Vasileios Kouranos,Simon Ward,Maria Kokosi,Diego Castillo,Felix Chua,Eoin P. Judge,Suzie Thomas,Frans van Tonder,A Devaraj,Andrew G. Nicholson,Toby M. Maher,Elisabetta A. Renzoni,Athol U. Wells +12 more
TL;DR: Mixed disease is present in approximately 25% of pulmonary sarcoidosis patients with airflow obstruction and is associated with lower DLco levels, a higher prevalence of stage IV disease and higher mortality than seen in a pure obstructive defect.
Journal ArticleDOI
Chromosomal translocations involving BCL6 in MALT lymphoma.
TL;DR: Chromosomal translocations involving BCL6 were detected in 7 out of 392 cases of MALT lymphoma by interphase fluorescence in situ hybridisation with a BCL 6 break-apart probe, with the exception of BCL7 protein expression in 2 of the 7 cases.