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Andrew G. Nicholson
Researcher at National Institutes of Health
Publications - 512
Citations - 87875
Andrew G. Nicholson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Lung cancer & Idiopathic pulmonary fibrosis. The author has an hindex of 113, co-authored 477 publications receiving 73860 citations. Previous affiliations of Andrew G. Nicholson include National Yang-Ming University & University College London.
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Regulation of TGF-1-induced connective tissue growth factor (CTGF) expression in airway smooth muscle cells
TL;DR: Transforming growth factor (TGF)-β may play an important role in airway remodeling, and the fibrogenic effect of TGF-β may be mediated through connective tissue growthFactor (CTGF) release.
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Terminal Diffuse Alveolar Damage in Relation to Interstitial Pneumonias
Alexandra Rice,Athol U. Wells,Demos Bouros,Roland M. du Bois,David M. Hansell,Vlasis Polychronopoulos,Dimitris A. Vassilakis,Jonathan R. Kerr,Timothy W. Evans,Andrew G. Nicholson +9 more
TL;DR: In this article, the authors reviewed autopsy material from patients who died of diffuse alveolar damage in the clinical setting of pulmonary fibrosis, both idiopathic and with background fibrosing alveolitis with connective tissue disorders (FA-CTDs), and compared them with cases of acute interstitial pneumonia.
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Antenatal and Postnatal Management of Congenital Cystic Adenomatoid Malformation
Sailesh Kotecha,Angelo Barbato,Andrew Bush,F. Claus,Mark Davenport,C. Delacourt,Jan Deprest,Ernst Eber,Björn Frenckner,Anne Greenough,Andrew G. Nicholson,Juan L. Antón-Pacheco,Fabio Midulla +12 more
TL;DR: There is an urgent need to delineate the natural history of antenatally detected CCAMs to guide future management and the potential of malignant transformation.
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Atypical goblet cell hyperplasia in congenital cystic adenomatoid malformation as a possible preneoplasia for pulmonary adenocarcinoma in childhood: a genetic analysis
Elvira Stacher,Reinhard Ullmann,Iris Halbwedl,Margit Gogg-Kammerer,Liliane Boccon-Gibod,Andrew G. Nicholson,Mary N. Sheppard,Lina Carvalho,Maria Teresa Franca,Fergus MacSweeney,Alicia Morresi-Hauf,Helmut Popper +11 more
TL;DR: Ch Chromosomal aberrations in AGCHs arising in CCAMs support their preneoplastic status, and the most frequent genomic imbalances observed in both AGCH and the carcinomas were gains in chromosomes 2 and 4.
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Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease
Gisela E. Lindahl,Carmel Stock,Xu Shiwen,Patricia Leoni,Piersante Sestini,Sarah L. Howat,George Bou-Gharios,Andrew G. Nicholson,Christopher P. Denton,Jan C. Grutters,Toby M. Maher,Athol U. Wells,David Abraham,Elisabetta A. Renzoni +13 more
TL;DR: The data suggests that the repressed expression of interferon-stimulated genes may underpin critical aspects of the profibrotic fibroblast phenotype, identifying an area in pulmonary fibrosis that requires further investigation.