A
Andrew Wolfe
Researcher at Johns Hopkins University School of Medicine
Publications - 219
Citations - 10029
Andrew Wolfe is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Gonadotropin-releasing hormone & Cache. The author has an hindex of 46, co-authored 217 publications receiving 9280 citations. Previous affiliations of Andrew Wolfe include International Monetary Fund & Princeton University.
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Power analysis of embedded software: a first step towards software power minimization
TL;DR: A power analysis technique is developed that has been applied to two commercial microprocessors and can be employed to evaluate the power cost of embedded software and can help in verifying if a design meets its specified power constraints.
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RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
Andrew Wolfe,Kamini Singh,Yi Zhong,Philipp Drewe,Vinagolu K. Rajasekhar,Viraj Sanghvi,Konstantinos J. Mavrakis,Man Jiang,Justine E. Roderick,Joni Van der Meulen,Jonathan H. Schatz,Christina M. Rodrigo,Chunying Zhao,Pieter Rondou,Elisa de Stanchina,Julie Teruya-Feldstein,Michelle A. Kelliher,Franki Speleman,John A. Porco,Jerry Pelletier,Gunnar Rätsch,Hans-Guido Wendel +21 more
TL;DR: An eIF4A RNA helicase-dependent mechanism of translational control that contributes to oncogenesis and underlies the anticancer effects of silvestrol and related compounds is reported.
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Instruction level power analysis and optimization of software
TL;DR: This paper describes an alternative, measurement based instruction level power analysis approach that provides an accurate and practical way of quantifying the power cost of soft-ware and guides the development of general tools and techniques for low power software.
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Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
Konstantinos J. Mavrakis,Andrew Wolfe,Andrew Wolfe,Elisa Oricchio,Teresa Palomero,Kim De Keersmaecker,Katherine McJunkin,Johannes Zuber,Johannes Zuber,Taneisha James,Kenneth Chang,Aly A. Khan,Aly A. Khan,Christina S. Leslie,Joel S. Parker,Patrick J. Paddison,Wayne Tam,Adolfo A. Ferrando,Hans-Guido Wendel +18 more
TL;DR: It is shown that miR-19 is sufficient to promote leukaemogenesis in Notch1-induced T-cell acute lymphoblastic leukaemia (T-ALL) in vivo and an unbiased, functional genomics approach reveals a coordinate clampdown on several regulators of phosphatidylinositol-3-OH kinase-related survival signals by theLeukaemogenic miR -19.
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Timing and completion of puberty in female mice depend on estrogen receptor α-signaling in kisspeptin neurons
Christian Mayer,Maricedes Acosta-Martinez,Sharon L. Dubois,Andrew Wolfe,Sally Radovick,Ulrich Boehm,Jon E. Levine,Jon E. Levine +7 more
TL;DR: It is shown that the temporal coordination of juvenile restraint and subsequent pubertal activation is likely mediated by ERα in two separate kisspeptin neuronal populations in the hypothalamus.