P
Pieter Rondou
Researcher at Ghent University
Publications - 32
Citations - 2158
Pieter Rondou is an academic researcher from Ghent University. The author has contributed to research in topics: Leukemia & Dopamine receptor. The author has an hindex of 21, co-authored 32 publications receiving 1865 citations. Previous affiliations of Pieter Rondou include Ghent University Hospital.
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Journal ArticleDOI
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
Andrew Wolfe,Kamini Singh,Yi Zhong,Philipp Drewe,Vinagolu K. Rajasekhar,Viraj Sanghvi,Konstantinos J. Mavrakis,Man Jiang,Justine E. Roderick,Joni Van der Meulen,Jonathan H. Schatz,Christina M. Rodrigo,Chunying Zhao,Pieter Rondou,Elisa de Stanchina,Julie Teruya-Feldstein,Michelle A. Kelliher,Franki Speleman,John A. Porco,Jerry Pelletier,Gunnar Rätsch,Hans-Guido Wendel +21 more
TL;DR: An eIF4A RNA helicase-dependent mechanism of translational control that contributes to oncogenesis and underlies the anticancer effects of silvestrol and related compounds is reported.
Journal ArticleDOI
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)
Konstantinos J. Mavrakis,Joni Van der Meulen,Andrew Wolfe,Andrew Wolfe,Xiaoping Liu,Evelien Mets,Tom Taghon,Aly A. Khan,Aly A. Khan,Manu Setty,Manu Setty,Pieter Rondou,Peter Vandenberghe,Eric Delabesse,Yves Benoit,Nicholas B Socci,Christina S. Leslie,Pieter Van Vlierberghe,Pieter Van Vlierberghe,Franki Speleman,Hans-Guido Wendel +20 more
TL;DR: A comprehensive and unbiased analysis of miRNA action in T-ALL reveals a striking pattern of mi RNA-tumor suppressor gene interactions in this cancer.
Journal ArticleDOI
The need for transparency and good practices in the qPCR literature
Stephen A. Bustin,Vladimir Benes,Jeremy A. Garson,Jan Hellemans,Jim F. Huggett,Mikael Kubista,Reinhold Mueller,Tania Nolan,Michael W. Pfaffl,Gregory L. Shipley,Carl T. Wittwer,Peter Schjerling,Philip J. R. Day,Mónica Abreu,Begoña Aguado,Jean-François Beaulieu,Anneleen Beckers,Sara Bogaert,John A. Browne,Fernando Carrasco-Ramiro,Liesbeth Ceelen,Kate L. Ciborowski,Pieter Cornillie,Stephanie Coulon,Ann Cuypers,Sara De Brouwer,Leentje De Ceuninck,Jurgen De Craene,Hélène De Naeyer,Ward De Spiegelaere,Kato Deckers,Annelies Dheedene,Kaat Durinck,Margarida Ferreira-Teixeira,Annelies Fieuw,Jack M. Gallup,Sandra Gonzalo-Flores,Karen Goossens,Femke Heindryckx,Elizabeth Herring,Hans Hoenicka,Laura Icardi,Rolf Jaggi,Farzad Javad,Michael Karampelias,Frederick S. B. Kibenge,Molly J. T. Kibenge,Candy Kumps,Irina Lambertz,Tim Lammens,Amelia Markey,Peter Messiaen,Evelien Mets,Sofia Morais,Alberto Mudarra-Rubio,Justine K. Nakiwala,Hilde Nelis,Pål A. Olsvik,Claudina Perez-Novo,Michelle Plusquin,Tony Remans,Ali Rihani,Paulo Rodrigues-Santos,Pieter Rondou,Rebecca Sanders,Katharina Schmidt-Bleek,Kerstin Skovgaard,Karen Smeets,Laura Tabera,Stefan Toegel,Tim Van Acker,Wim Van den Broeck,Joni Van der Meulen,Mireille Van Gele,Gert Van Peer,Mario Van Poucke,Nadine Van Roy,Sarah Vergult,Joris Wauman,Marina Tshuikina-Wiklander,Erik Willems,Sara Zaccara,Fjoralba Zeka,Jo Vandesompele +83 more
TL;DR: Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR) reveal a lack of transparent and comprehensive reporting of essential technical information.
Journal ArticleDOI
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
Joni Van der Meulen,Viraj Sanghvi,Konstantinos J. Mavrakis,Kaat Durinck,Fang Fang,Filip Matthijssens,Pieter Rondou,Monica Rosen,Tim Pieters,Peter Vandenberghe,Eric Delabesse,Tim Lammens,Barbara De Moerloose,Björn Menten,Nadine Van Roy,Bruno Verhasselt,Bruce Poppe,Yves Benoit,Tom Taghon,Ari Melnick,Franki Speleman,Hans-Guido Wendel,Pieter Van Vlierberghe +22 more
TL;DR: In this paper, the X-linked histone H3K27me3 demethylase ubiquitously transcribed X (UTX) chromosome was found to be a bona fide tumor suppressor in T-ALL.
Journal ArticleDOI
The dopamine D4 receptor: biochemical and signalling properties
TL;DR: This work focuses on the dopamine D4 receptor, which contains an important polymorphism in its third intracellular loop and has been the subject of numerous studies investigating links with several brain disorders, such as attention-deficit hyperactivity disorder and schizophrenia.