A
Ann A. Jakubowski
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 283
Citations - 13559
Ann A. Jakubowski is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 51, co-authored 261 publications receiving 12186 citations. Previous affiliations of Ann A. Jakubowski include Amgen & Northwestern University.
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Journal ArticleDOI
Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid).
Raymond P. Warrell,Stanley R. Frankel,Wilson H. Miller,David A. Scheinberg,Loretta M. Itri,Walter N. Hittelman,Rohini Vyas,Michael Andreeff,Agostino Tafuri,Ann A. Jakubowski,Janice Gabrilove,Michael Gordon,Ethan Dmitrovsky +12 more
TL;DR: Tretinoin is a safe and highly effective agent for inducing complete remission in patients with acute promyelocytic leukemia and clinical response to this agent is associated with leukemic-cell differentiation and is linked to the expression of an aberrant RAR-alpha nuclear receptor.
Journal ArticleDOI
Effect of Granulocyte Colony-Stimulating Factor on Neutropenia and Associated Morbidity Due to Chemotherapy for Transitional-Cell Carcinoma of the Urothelium
Janice Gabrilove,Ann A. Jakubowski,Ann A. Jakubowski,Howard I. Scher,Howard I. Scher,Cora N. Sternberg,Cora N. Sternberg,George Y. Wong,George Y. Wong,John Grous,John Grous,Alan Yagoda,Alan Yagoda,K. Fain,K. Fain,Malcolm A.S. Moore,Malcolm A.S. Moore,Bayard D. Clarkson,Bayard D. Clarkson,Herbert F. Oettgen,Herbert F. Oettgen,Kirby Alton,Kirby Alton,Karl Welte,Karl Welte,Lawrence M. Souza,Lawrence M. Souza +26 more
TL;DR: It is demonstrated that rhG-CSF is a potent stimulus of normal neutrophil proliferation and maturation and its administration can reduce both the hematopoietic and oral toxicity of chemotherapy.
Journal ArticleDOI
Developing a Cancer-Specific Geriatric Assessment: A Feasibility Study
Arti Hurria,Supriya Gupta,Marjorie G. Zauderer,Enid L. Zuckerman,Harvey J. Cohen,Hyman B. Muss,Miriam B. Rodin,Katherine S. Panageas,Jimmie C. Holland,Leonard B. Saltz,Mark G. Kris,Ariela Noy,Jorge Gomez,Ann A. Jakubowski,Clifford A. Hudis,Alice B. Kornblith +15 more
TL;DR: A brief, but comprehensive, primarily self‐administered cancer‐specific geriatric assessment measure is developed and its feasibility is determined as measured by the percentage of patients able to complete the measure on their own, the length of time to complete, and patient satisfaction with the measure.
Journal ArticleDOI
Use of Epoetin in Patients With Cancer: Evidence-Based Clinical Practice Guidelines of the American Society of Clinical Oncology and the American Society of Hematology
J. Douglas Rizzo,Alan E. Lichtin,Steven H. Woolf,Jerome Seidenfeld,Charles L. Bennett,David Cella,Benjamin Djulbegovic,Matthew J. Goode,Ann A. Jakubowski,Stephanie J. Lee,Carole B. Miller,Mark U. Rarick,David H. Regan,George P. Browman,Michael S. Gordon +14 more
TL;DR: It is recommended that physicians initiate conventional therapy and observe hematologic response before considering use of epoetin for anemic patients withHematologic malignancies.
Journal ArticleDOI
Comparison of immune reconstitution after unrelated and related T-cell-depleted bone marrow transplantation : Effect of patient age and donor leukocyte infusions
Trudy N. Small,Esperanza B. Papadopoulos,Farid Boulad,P Black,Hugo Castro-Malaspina,Barrett H. Childs,Nancy H. Collins,Alfred P. Gillio,Daniel J. George,Ann A. Jakubowski,Glenn Heller,Melissa Fazzari,Nancy A. Kernan,Stephen Mackinnon,Paul Szabolcs,James W. Young,R.J. O'Reilly +16 more
TL;DR: It is demonstrated that adult recipients of TCD unrelated BMTs experience prolonged and profound deficiencies of CD3(+, CD4(+), and CD8(+) T-cell populations when compared with pediatric recipients of unrelated B MT and adults after related BMT, and that these adults have a significantly increased risk of life-threatening opportunistic infections.