Anna Collin

TL;DR: The primary clinical applications for FISH analysis were for newly diagnosed cases of MM or frank relapse cases and prospective analysis should be centralized for upcoming trials based on the recommendations made.

TL;DR: The hypothesis that the NAB2/STAT6 fusions will result in altered properties of the transcriptional co‐repressor NAB 2 ‐ a key regulator of the early growth response 1 (EGR1) transcription factor – was corroborated by global gene expression analysis; SFTs showed deregulated expression of EGR1 target genes, as well as of other, developmentally important genes.

TL;DR: Correlation with clinical features revealed that lipomas with rings/giant markers were larger, occurred in older patients, were more often deep‐seated, and seemed to have an increased tendency to recur locally, compared with tumors with other chromosome aberrations.

TL;DR: The generation of a comprehensive library of iPSC lines of familial PD and an associated synucleinopathy, multiple system atrophy is reported, which will be a valuable resource for identifying common and divergent mechanisms leading to neurodegeneration in PD and MSA.

TL;DR: It is shown that a putative POU5F1P1 protein is localized in the nucleus, acts as a transcriptional activator and regulates the expression in a similar way to the POU4F1 isoform 1, but was a weaker activator than isoforms 1 and 2.