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Anne Wojtusciszyn
Researcher at University of Lausanne
Publications - 73
Citations - 1780
Anne Wojtusciszyn is an academic researcher from University of Lausanne. The author has contributed to research in topics: Transplantation & Islet. The author has an hindex of 20, co-authored 59 publications receiving 1401 citations. Previous affiliations of Anne Wojtusciszyn include Geneva College & French Institute of Health and Medical Research.
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Journal ArticleDOI
Toward Defining the Threshold Between Low and High Glucose Variability in Diabetes
Louis Monnier,Claude Colette,Anne Wojtusciszyn,Sylvie Dejager,Eric Renard,Nicolas Molinari,David R. Owens +6 more
TL;DR: A %CV of 36% appears to be a suitable threshold to distinguish between stable and unstable glycemia in diabetes because beyond this limit, the frequency of hypoglycemia is significantly increased, especially in insulin-treated subjects.
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The contribution of glucose variability to asymptomatic hypoglycemia in persons with type 2 diabetes.
TL;DR: As the risk of asymptomatic hypoglycemia increases in the presence of increased glucose variability, avoidance of excess glucose fluctuations should be an important consideration for either reducing or preventing the risk in type 2 diabetes.
Journal ArticleDOI
Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts
Anne Wojtusciszyn,Anne Wojtusciszyn,Mathieu Pierre Jean Armanet,Philippe Morel,Thierry Berney,Domenico Bosco +5 more
TL;DR: Human beta cells are highly heterogeneous in terms of insulin secretion so that a small fraction of beta cells contributes to the majority of insulin secreted.
Journal ArticleDOI
Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial
Sandrine Lablanche,Sandrine Lablanche,Marie-Christine Vantyghem,Laurence Kessler,Anne Wojtusciszyn,Sophie Borot,C. Thivolet,Sophie Girerd,Domenico Bosco,Jean-Luc Bosson,Cyrille Colin,Cyrille Colin,Rachel Tetaz,Sophie Logerot,Julie Kerr-Conte,Eric Renard,Alfred Penfornis,Emmanuel Morelon,Fanny Buron,Kristina Skaare,Gwen Grguric,Gwen Grguric,Coralie Camillo-Brault,Coralie Camillo-Brault,Harald Egelhofer,Kanza Benomar,Lionel Badet,Thierry Berney,François Pattou,Pierre-Yves Benhamou,Pierre-Yves Benhamou,Paolo Malvezzi,Igor Tauveron,Béatrice Roche,Christian Noel,Luc Frimat,Bruno Guerci,Nadine Pernin,Anaïck Moisan,Virginie Persoons,Rimed Ezzouaoui,Valery Gmyr,Frédéric Thony,Yvan Bricault,Mathieu Rodière,Christian Sengel,M. Greget,Iulian Enescu,Marc Hazzan,R. Caiazzo,Fanelly Torres,Kristel Le Mapihan,Violetta Raverdy,Marie-Ange Pierredon,Pierre-Jean Valette,Arnaud Muller,Jean Champagnac,Lucy Chaillous,Jacques Dantal,Pierre Cattan,Jean-Pierre Riveline,François Moreau,Philippe Baltzinger,Thibault Bahoune +63 more
TL;DR: For the indications assessed in this study, islet transplantation effectively improves metabolic outcomes and seems to be a valid option for patients with severe, unstable type 1 diabetes who are not responding to intensive medical treatments.
Journal ArticleDOI
Five-Year Metabolic, Functional, and Safety Results of Patients With Type 1 Diabetes Transplanted With Allogenic Islets Within the Swiss-French GRAGIL Network
Sandrine Lablanche,Sophie Borot,Anne Wojtusciszyn,François Bayle,Rachel Tetaz,Lionel Badet,Charles Thivolet,Emmanuel Morelon,Luc Frimat,Alfred Penfornis,Laurence Kessler,Coralie Brault,Cyrille Colin,Igor Tauveron,Domenico Bosco,Thierry Berney,Pierre-Yves Benhamou +16 more
TL;DR: In a large cohort with a 5-year follow-up and in a multicenter network setting, islet transplantation was safe and efficient in restoring good and lasting glycemic control and preventing severe hypoglycemia in patients with type 1 diabetes.