B
Bei Jung Lin
Researcher at National Yang-Ming University
Publications - 7
Citations - 549
Bei Jung Lin is an academic researcher from National Yang-Ming University. The author has contributed to research in topics: Calcium imaging & Region of interest. The author has an hindex of 7, co-authored 7 publications receiving 378 citations. Previous affiliations of Bei Jung Lin include Howard Hughes Medical Institute & University of Göttingen.
Papers
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Journal ArticleDOI
Bright and photostable chemigenetic indicators for extended in vivo voltage imaging.
Ahmed S. Abdelfattah,Takashi Kawashima,Amrita Singh,Amrita Singh,Ondrej Novak,Ondrej Novak,Hui Liu,Yichun Shuai,Yi Chieh Huang,Luke Campagnola,Stephanie C. Seeman,Jianing Yu,Jihong Zheng,Jonathan B. Grimm,Ronak Patel,Johannes Friedrich,Brett D. Mensh,Liam Paninski,John J. Macklin,Gabe J. Murphy,Kaspar Podgorski,Bei Jung Lin,Tsai Wen Chen,Glenn C. Turner,Zhe Liu,Minoru Koyama,Karel Svoboda,Misha B. Ahrens,Luke D. Lavis,Eric R. Schreiter +29 more
TL;DR: A GEVI is engineered, called Voltron, that uses bright and photostable synthetic dyes instead of protein-based fluorophores, thereby extending the number of neurons imaged simultaneously in vivo by a factor of 10 and enabling imaging for significantly longer durations relative to existing GEVIs.
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A comparison of neuronal population dynamics measured with calcium imaging and electrophysiology.
Ziqiang Wei,Ziqiang Wei,Bei Jung Lin,Bei Jung Lin,Tsai Wen Chen,Tsai Wen Chen,Kayvon Daie,Karel Svoboda,Shaul Druckmann,Shaul Druckmann +9 more
TL;DR: This work compared neuronal spikes and fluorescence in matched neural populations in behaving mice and developed a model transforming spike trains to synthetic-imaging data, which highlights challenges in relating electrophysiology and imaging data and suggests forward modeling as an effective way to understand differences between these data.
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Odor coding by modules of coherent mitral/tufted cells in the vertebrate olfactory bulb.
TL;DR: At the output stage of the OB, odors are represented by modules of distributed and synchronous M/T cells associated with the same glomeruli, which allows for parallel input to higher brain centers.
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In Situ Background Estimation in Quantitative Fluorescence Imaging
TL;DR: A novel method is described that determined the background of a given region of interest (ROI) using the information contained in the temporal dynamics of its individual pixels and extended to deal with background inhomogeneities within a single ROI, a problem not yet solved by any of the currently available tools.
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Cell type-specific relationships between spiking and [Ca2+]i in neurons of the Xenopus tadpole olfactory bulb.
TL;DR: The results demonstrate that the relationship between somatic [Ca2+]i and APs can be cell type specific, and fast calcium imaging is an extremely valuable tool for determining spatiotemporal patterns of APs in neuronal population.