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Belén Navia
Researcher at University of Santiago de Compostela
Publications - 4
Citations - 444
Belén Navia is an academic researcher from University of Santiago de Compostela. The author has contributed to research in topics: Energy homeostasis & Neuropeptide. The author has an hindex of 4, co-authored 4 publications receiving 377 citations.
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Journal ArticleDOI
TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins
Víctor M. Meseguer,Yeranddy A. Alpizar,Enoch Luis,Sendoa Tajada,Bristol Denlinger,Otto Fajardo,Jan-Albert Manenschijn,Carlos Fernández-Peña,Arturo Talavera,Tatiana Kichko,Belén Navia,Alicia Sanchez,Rosa Señarís,Peter W. Reeh,M. T. Pérez-García,José R. López-López,Thomas Voets,Carlos Belmonte,Karel Talavera,Félix Viana +19 more
TL;DR: This work shows that LPS exerts fast, membrane delimited, excitatory actions via TRPA1, a transient receptor potential cation channel that is critical for transducing environmental irritant stimuli into nociceptor activity, and finds that pain and acute vascular reactions, including neurogenic inflammation (CGRP release) caused by LPS are primarily dependent onTRPA1 channel activation in nocICEptive sensory neurons, and develop independently of TLR4 activation.
Journal ArticleDOI
Interleukin-6 regulates the expression of hypothalamic neuropeptides involved in body weight in a gender-dependent way.
Rosa Señarís,Martha L. Trujillo,Belén Navia,Gemma Comes,Beatriz Ferrer,M. Giralt,Juan Hidalgo +6 more
TL;DR: It is demonstrated that IL‐6 may regulate the expression of hypothalamic neuropeptides involved in the control of body weight and body fat acting at the central level in a gender‐ and age‐dependent way.
Journal ArticleDOI
Muscle-specific interleukin-6 deletion influences body weight and body fat in a sex-dependent manner
Beatriz Ferrer,Belén Navia,Mercedes Giralt,Gemma Comes,Javier Carrasco,Amalia Molinero,Albert Quintana,Rosa Señarís,Juan Hidalgo +8 more
TL;DR: It is demonstrated that muscle IL-6 controls body weight and body fat in a sex-specific fashion, influencing the expression of the main neuropeptides involved in energy homeostasis.
Journal ArticleDOI
Interleukin-6 deletion in mice driven by aP2-Cre-ERT2 prevents against high-fat diet-induced gain weight and adiposity in female mice
Belén Navia,Beatriz Ferrer,M. Giralt,Gemma Comes,Javier Carrasco,Amalia Molinero,Albert Quintana,Jocelyne Leclerc,Jocelyne Leclerc,Jocelyne Leclerc,Benoit Viollet,Benoit Viollet,Benoit Viollet,Rosa Señarís,Juan Hidalgo +14 more
TL;DR: The aim of this study was to analyse the effects of tissue‐specific deletion of IL‐6 using a fatty acid binding protein (aP2) promoter‐Cre inducible system ( aP2‐Cre‐ERT2)