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Beverley A. Orser
Researcher at University of Toronto
Publications - 207
Citations - 14148
Beverley A. Orser is an academic researcher from University of Toronto. The author has contributed to research in topics: GABAA receptor & Receptor. The author has an hindex of 57, co-authored 189 publications receiving 12568 citations. Previous affiliations of Beverley A. Orser include University of Colorado Denver & University of New Mexico.
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Journal ArticleDOI
Communication failures in the operating room: an observational classification of recurrent types and effects
Lorelei Lingard,Sherry Espin,Sarah Whyte,Glenn Regehr,G. R. Baker,R. Reznick,John M.A. Bohnen,Beverley A. Orser,Diane Doran,E. Grober +9 more
TL;DR: Communication failures in the OR exhibited a common set of problems and a third of these resulted in effects which jeopardized patient safety by increasing cognitive load, interrupting routine, and increasing tension in the Or.
Journal ArticleDOI
Evaluation of a preoperative checklist and team briefing among surgeons, nurses, and anesthesiologists to reduce failures in communication
Lorelei Lingard,Glenn Regehr,Beverley A. Orser,Richard K. Reznick,G. Ross Baker,Diane Doran,Sherry Espin,John M.A. Bohnen,Sarah Whyte +8 more
TL;DR: Interprofessional checklist briefings reduced the number of communication failures and promoted proactive and collaborative team communication in general surgery at a Canadian academic tertiary care hospital.
Journal ArticleDOI
Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by α5 subunit-containing γ-aminobutyric acid type A receptors
Valerie B. Caraiscos,Erin M. Elliott,Kong E. You-Ten,Victor Y. Cheng,Delia Belelli,J. Glen Newell,Michael F. Jackson,Jeremy J. Lambert,Thomas W. Rosahl,Keith A. Wafford,John F. MacDonald,Beverley A. Orser +11 more
TL;DR: The results suggest that tonic inhibition mediated by α5GABAARs in hippocampal pyramidal neurons plays a key role in cognitive processes.
Journal ArticleDOI
Emerging molecular mechanisms of general anesthetic action
Hugh C. Hemmings,Myles H. Akabas,Peter A. Goldstein,James R. Trudell,Beverley A. Orser,Neil L. Harrison +5 more
TL;DR: These developments, which have important implications for the development of more-selective anesthetics, are reviewed in the context of recent advances in ion channel structure and function.
Journal ArticleDOI
Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery—2018
L. Evered,L. Evered,B. Silbert,B. Silbert,D. S. Knopman,D.A. Scott,D.A. Scott,S.T. DeKosky,L.S. Rasmussen,E.S. Oh,Gregory Crosby,M. Berger,R. Eckenhoff,Lisbeth Evered,Roderic G. Eckenhoff,David Ames,Alex Bekker,Miles Berger,Deborah Blacker,Jeffrey N. Browndyke,G. Crosby,Stacie Deiner,Diederik van Dijk,Steven T. DeKosky,Maryellen F. Eckenhoff,Lars Eriksson,Dougas Galasko,Kirk J. Hogan,Sharon K. Inouye,David S. Knopman,Constantine G. Lyketsos,Edward R. Marcantonio,Paul Maruff,Mervyn Maze,Esther S. Oh,Beverley A. Orser,Thomas H. Ottens,Catherine Price,Lars S. Rasmussen,Perminder S. Sachdev,Katie J. Schenning,David Scott,Frederick E. Seiber,Brendan S. Silbert,Jeffrey H. Silverstein,Jacob Steinmetz,Niccolò Terrando,Paula Trzapacz,Rob Whittington,Zhongcong Xie +49 more
TL;DR: The working group recommends that ‘perioperative neurocognitive disorders’ be used as an overarching term for cognitive impairment identified in the preoperative or postoperative period as well as two major classification guidelines used outside of anaesthesia and surgery.