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Brendan S. Silbert

Researcher at St. Vincent's Health System

Publications -  146
Citations -  7921

Brendan S. Silbert is an academic researcher from St. Vincent's Health System. The author has contributed to research in topics: Postoperative cognitive dysfunction & Cognitive decline. The author has an hindex of 42, co-authored 134 publications receiving 6258 citations. Previous affiliations of Brendan S. Silbert include RMIT University & Copenhagen University Hospital.

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Epidural anaesthesia and analgesia and outcome of major surgery: a randomised trial

TL;DR: Most adverse morbid outcomes in high-risk patients undergoing major abdominal surgery are not reduced by use of combined epidural and general anaesthesia and postoperative epidural analgesia, however, the improvement in analgesIA, reduction in respiratory failure, and the low risk of serious adverse consequences suggest that many high- risk patients undergo major intra-abdominal surgery will receive substantial benefit from combined general and epidural anaesthesia intraoperatively with continuing postoperative analgesia.
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Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery—2018

TL;DR: The working group recommends that ‘perioperative neurocognitive disorders’ be used as an overarching term for cognitive impairment identified in the preoperative or postoperative period as well as two major classification guidelines used outside of anaesthesia and surgery.
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Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery—2018

L. Evered, +49 more
TL;DR: The working group recommends that ‘perioperative neurocognitive disorders’ be used as an overarching term for cognitive impairment identified in the preoperative or postoperative period as well as two major classification guidelines used outside of anaesthesia and surgery.
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Avoidance of nitrous oxide for patients undergoing major surgery - A randomized controlled trial

TL;DR: In this article, the authors compared the use of nitrous oxide-free and N2O-based anesthesia in patients undergoing major surgery and found that the latter significantly decreased the incidence of complications after major surgery, while the latter increased the inspired oxygen concentration.
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Postoperative cognitive dysfunction is independent of type of surgery and anesthetic.

TL;DR: The incidence of Postoperative cognitive dysfunction in old and elderly patients at day 7 was higher after CABG surgery than THJR surgery, but POCD at 3 months was independent of the nature or the type of procedure or anesthetic when comparing CA, THJR, and C ABG surgery groups.