Bilal A. Moiz

TL;DR: Three genome-wide significant linked variants on 11p for myopia in Caucasians are identified and 11p is a promising region that has been identified by other linkage studies with a number of potentially interesting candidate genes.

TL;DR: Agarwal et al. as mentioned in this paper performed whole exome sequencing on 262 individuals from 28 extended families with a family history of lung cancer and found that regions on 12q, 7p, and 4q are linked to increased cancer risk in highly aggregated lung cancer families.

TL;DR: Using functional annotation, the authors were able to identify several rare nonsynonymous variants that were enriched in each family that caused Chiari I malformation and found a genome-wide significant signal on chromosome 1q43-44.

TL;DR: A significant genetic linkage between myopia and Han Chinese patients at 10q26.13 is reported, which contains several good candidate genes, such as TACC2 and the known age-related macular degeneration gene HTRA1.

TL;DR: 2 novel linkage peaks for myopia on chromosomes 7 and 8 in these Ashkenazi Jewish families are identified and 2 more loci on chromosomes 1 and 11 are replicated, one previously reported in refractive error but not myopia in these families and the other locusPreviously reported in the literature.