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Bing Hou
Researcher at University of Leeds
Publications - 9
Citations - 1266
Bing Hou is an academic researcher from University of Leeds. The author has contributed to research in topics: Voltage-dependent calcium channel & Vascular endothelial growth factor A. The author has an hindex of 7, co-authored 9 publications receiving 877 citations. Previous affiliations of Bing Hou include St James's University Hospital.
Papers
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Journal ArticleDOI
Piezo1 integration of vascular architecture with physiological force
Jing Li,Bing Hou,Sarka Tumova,Katsuhiko Muraki,Alexander F. Bruns,Melanie J. Ludlow,Alicia Sedo,Adam J. Hyman,Lynn McKeown,Richard S. Young,Richard S. Young,Nadira Yuldasheva,Yasser Majeed,Lesley A. Wilson,Baptiste Rode,Marc A. Bailey,Hyejeong R. Kim,Zhaojun Fu,Deborah Angela Louise Carter,Jan Bilton,Helen Imrie,Paul Ajuh,T. Neil Dear,Richard M Cubbon,Mark T. Kearney,K. Raj Prasad,Paul C. Evans,Justin F. X. Ainscough,David J. Beech +28 more
TL;DR: Piezo1 channels are shown as sensors of frictional force (shear stress) and determinants of vascular structure in both development and adult physiology and the data suggest that Piezo 1 channels function as pivotal integrators in vascular biology.
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Orai1 and CRAC Channel Dependence of VEGF-Activated Ca2+ Entry and Endothelial Tube Formation
Jing Li,Richard M Cubbon,Lesley A. Wilson,Mohamed S Amer,Mohamed S Amer,Lynn McKeown,Bing Hou,Yasser Majeed,Sarka Tumova,Victoria A.L. Seymour,Hilary Taylor,Martin Stacey,David J. O'Regan,Richard Foster,Karen E. Porter,Mark T. Kearney,David J. Beech +16 more
TL;DR: Positive roles for Orai1 and CRAC channels in VEGF-evoked calcium entry and new opportunity for chemical modulation of angiogenesis are suggested.
Journal ArticleDOI
Piezo1 Integration of Vascular Architecture with Physiological Force
TL;DR: The mechanisms by which physical forces regulate endothelial cells to determine the complexities of vascular structure and function are enigmatic as mentioned in this paper, and it has been suggested that sensory neurons have suggested Piezo pr...
Journal ArticleDOI
Pregnenolone Sulphate- and Cholesterol-Regulated TRPM3 Channels Coupled to Vascular Smooth Muscle Secretion and Contraction
Jacqueline Naylor,Jing Li,Carol J. Milligan,Fanning Zeng,Piruthivi Sukumar,Bing Hou,Alicia Sedo,Nadira Yuldasheva,Yasser Majeed,Dhananjay Beri,Shan Jiang,Victoria A.L. Seymour,Lynn McKeown,Bhaskar Kumar,Christian Harteneck,David J. O'Regan,Stephen B. Wheatcroft,Mark T. Kearney,Clare A. Jones,Karen E. Porter,David J. Beech +20 more
TL;DR: The data suggest functional relevance of TRPM3 in contractile and proliferating phenotypes of vascular smooth muscle cells, significance of constitutive channel activity, regulation by cholesterol, and potential value of pregnenolone sulfate in therapeutic vascular modulation.
Journal ArticleDOI
Inhibition of endothelial cell Ca2+ entry and transient receptor potential channels by Sigma‐1 receptor ligands
Mohamed S Amer,Lynn McKeown,Sarka Tumova,Ruifeng Liu,Victoria A.L. Seymour,Lesley A. Wilson,Jacqueline Naylor,Katriona Greenhalgh,Bing Hou,Yasser Majeed,Paul Turner,Alicia Sedo,David J. O'Regan,Jing Li,Robin S. Bon,Karen E. Porter,David J. Beech +16 more
TL;DR: This study investigated Sig1R and its ligands in relation to endogenous calcium events of endothelial cells and transient receptor potential (TRP) channels.