J
Justin F. X. Ainscough
Researcher at University of Leeds
Publications - 48
Citations - 3013
Justin F. X. Ainscough is an academic researcher from University of Leeds. The author has contributed to research in topics: Genomic imprinting & Gene. The author has an hindex of 26, co-authored 47 publications receiving 2473 citations. Previous affiliations of Justin F. X. Ainscough include University of York & University of Cambridge.
Papers
More filters
Journal ArticleDOI
Piezo1 integration of vascular architecture with physiological force
Jing Li,Bing Hou,Sarka Tumova,Katsuhiko Muraki,Alexander F. Bruns,Melanie J. Ludlow,Alicia Sedo,Adam J. Hyman,Lynn McKeown,Richard S. Young,Richard S. Young,Nadira Yuldasheva,Yasser Majeed,Lesley A. Wilson,Baptiste Rode,Marc A. Bailey,Hyejeong R. Kim,Zhaojun Fu,Deborah Angela Louise Carter,Jan Bilton,Helen Imrie,Paul Ajuh,T. Neil Dear,Richard M Cubbon,Mark T. Kearney,K. Raj Prasad,Paul C. Evans,Justin F. X. Ainscough,David J. Beech +28 more
TL;DR: Piezo1 channels are shown as sensors of frictional force (shear stress) and determinants of vascular structure in both development and adult physiology and the data suggest that Piezo 1 channels function as pivotal integrators in vascular biology.
Journal ArticleDOI
H19 acts as a trans regulator of the imprinted gene network controlling growth in mice
Anne Gabory,Marie-Anne Ripoche,Anne Le Digarcher,Françoise Watrin,Ahmed Ziyyat,Thierry Forné,Hélène Jammes,Justin F. X. Ainscough,M. Azim Surani,Laurent Journot,Luisa Dandolo +10 more
TL;DR: It is proposed that the H19 gene participates as a trans regulator in the fine-tuning of this imprinted gene network in the mouse embryo, which is the first in vivo evidence of a functional role for the H 19 RNA.
Journal ArticleDOI
Piezo1 Integration of Vascular Architecture with Physiological Force
TL;DR: The mechanisms by which physical forces regulate endothelial cells to determine the complexities of vascular structure and function are enigmatic as mentioned in this paper, and it has been suggested that sensory neurons have suggested Piezo pr...
Journal Article
Imprinting of Igf2 and H19 from a 130 kb YAC transgene
TL;DR: A novel model is proposed in which silencing of the H19 gene is the default state and its activation after maternal inheritance is the key mechanistic event for imprinting in this region.
Journal ArticleDOI
Pluripotential stem cells derived from migrating primordial germ cells
TL;DR: Four EGC lines from migrating PGCs of 9.5 days post coitum embryos showed properties that were similar to previously established EGC Lines, including colony morphology, expression of alkaline phosphatase (AP), and expression of SSEA-1 antigen, and the methylation status of the imprinted genes were examined.