B
Booki Min
Researcher at Cleveland Clinic
Publications - 95
Citations - 5435
Booki Min is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: T cell & Cytotoxic T cell. The author has an hindex of 38, co-authored 86 publications receiving 5045 citations. Previous affiliations of Booki Min include Cleveland Clinic Lerner College of Medicine & National Institutes of Health.
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Journal ArticleDOI
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.
Jinfang Zhu,Booki Min,Jane Hu-Li,Cynthia J. Watson,Alex Grinberg,Qi Wang,Nigel Killeen,Joseph F. Urban,Liying Guo,William E. Paul +9 more
TL;DR: In vivo deletion of Gata3 using OX40-Cre eliminated TH2 responses and allowed the development of interferon-γ-producing cells in mice infected with Nippostrongylus brasiliensis, indicating that GATA-3 serves as a principal switch in determining TH1-TH2 responses.
Journal ArticleDOI
Basophils Produce IL-4 and Accumulate in Tissues after Infection with a Th2-inducing Parasite
Booki Min,Melanie Prout,Jane Hu-Li,Jinfang Zhu,Dragana Jankovic,Ellen S. Morgan,Joseph F. Urban,Ann M. Dvorak,Fred D. Finkelman,Graham LeGros,William E. Paul +10 more
TL;DR: Infection with a parasite that induces a “Th2-type response” resulted in accumulation of tissue basophils, and these cells, stimulated by a non-FcR cross-linking mechanism, are a principal source of in vivo IL-4 production.
Journal ArticleDOI
Neonates Support Lymphopenia-Induced Proliferation
Booki Min,Rebecca S. McHugh,Gregory D. Sempowski,Crystal L. Mackall,Gilles Foucras,William E. Paul +5 more
TL;DR: Lymphopenia-induced T cell proliferation is a physiologic process that occurs during the early postnatal period and naive CD4 T cells that proliferate within neonates acquire the phenotypic and functional characteristics of memory cells.
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A critical role for IRAK4 kinase activity in Toll-like receptor–mediated innate immunity
Tae Whan Kim,Kirk A. Staschke,Katarzyna Bulek,Jianhong Yao,Kristi L. Peters,Keunhee Oh,Yvonne Vandenburg,Hui Xiao,Wen Qian,Thomas A. Hamilton,Booki Min,Ganes C. Sen,Raymond Gilmour,Xiaoxia Li +13 more
TL;DR: Results indicate that IRAK4 kinase activity plays a critical role in TLR-dependent immune responses and reduces cytokine and chemokine production in bone marrow–derived macrophages from IRAK 4 kinase–inactive knock-in mice.
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Growth Factor Independent-1 Induced by IL-4 Regulates Th2 Cell Proliferation
Jinfang Zhu,Liying Guo,Booki Min,Cynthia J. Watson,Jane Hu-Li,Howard A. Young,Philip N. Tsichlis,William E. Paul +7 more
TL;DR: It is reported that growth factor independent-1 (Gfi-1), a Stat6-dependent transcriptional repressor, strikingly increases Th2 cell expansion by promoting proliferation and preventing apoptosis.