B
Brian P. Anton
Researcher at New England Biolabs
Publications - 55
Citations - 2044
Brian P. Anton is an academic researcher from New England Biolabs. The author has contributed to research in topics: Genome & Restriction enzyme. The author has an hindex of 19, co-authored 52 publications receiving 1906 citations. Previous affiliations of Brian P. Anton include Hannover Medical School & Boston University.
Papers
More filters
Journal Article
Draft genome of the filarial nematode parasite Brugia malayi (Science (2007) (1756))
TL;DR: Comparative analysis with the free-living, model nematode Caenorhabditis elegans revealed that, despite these genes having maintained little conservation of local synteny during ∼350 million years of evolution, they largely remain in linkage on chromosomal units.
Journal ArticleDOI
The methylomes of six bacteria
Iain A. Murray,Tyson A. Clark,Richard D. Morgan,Matthew Boitano,Brian P. Anton,Khai Luong,Alexey Fomenkov,Stephen Turner,Jonas Korlach,Richard J. Roberts +9 more
TL;DR: This study shows that the addition of SMRT sequencing to traditional sequencing approaches gives a wealth of useful functional information about a genome showing not only which MTase genes are active but also revealing their recognition sequences.
Journal ArticleDOI
The COMBREX Project: Design, Methodology, and Initial Results
Brian P. Anton,Yi Chien Chang,Peter Brown,Han-Pil Choi,Lina L. Faller,Jyotsna Guleria,Zhenjun Hu,Niels Klitgord,Ami Levy-Moonshine,Almaz Maksad,Varun Mazumdar,Mark G. McGettrick,Lais Osmani,Revonda M. Pokrzywa,John Rachlin,Rajeswari Swaminathan,Benjamin L. Allen,Benjamin L. Allen,Genevieve Housman,Caitlin Monahan,Krista Rochussen,Kevin R. Tao,Ashok S. Bhagwat,Steven E. Brenner,Linda Columbus,Valérie de Crécy-Lagard,Donald J. Ferguson,Alexey Fomenkov,Giovanni Gadda,Richard D. Morgan,Andrei L. Osterman,Dmitry A. Rodionov,Irina A. Rodionova,Kenneth E. Rudd,Dieter Söll,Jim C. Spain,Shuang-yong Xu,Alex Bateman,Robert Blumenthal,J. Martin Bollinger,Woo Suk Chang,Manuel Ferrer,Iddo Friedberg,Michael Y. Galperin,Julien Gobeill,Julien Gobeill,Daniel H. Haft,John F. Hunt,Peter D. Karp,William Klimke,Carsten Krebs,Dana Macelis,Ramana Madupu,Maria Jesus Martin,Jeffrey H Miller,Claire O'Donovan,Bernhard O. Palsson,Patrick Ruch,Patrick Ruch,Aaron T. Setterdahl,Granger G. Sutton,John Tate,Alexander F. Yakunin,Dmitri Tchigvintsev,Germán Plata,Jie Hu,Russell Greiner,David Horn,Kimmen Sjölander,Steven L. Salzberg,Dennis Vitkup,Stanley Letovsky,Daniel Segrè,Charles DeLisi,Richard J. Roberts,Richard J. Roberts,Martin Steffen,Simon Kasif +77 more
TL;DR: This community page discusses the progress made by the COMBREX project to address this important issue using both computational and experimental resources.
Journal ArticleDOI
The Complete Genome of Teredinibacter turnerae T7901: An Intracellular Endosymbiont of Marine Wood-Boring Bivalves (Shipworms)
Joyce C. Yang,Ramana Madupu,A. Scott Durkin,Nathan A. Ekborg,Chandra Sekhar Pedamallu,Jessica B. Hostetler,Diana Radune,Bradley S. Toms,Bernard Henrissat,Pedro M. Coutinho,Sandra Schwarz,Lauren Field,Amaro E. Trindade-Silva,Carlos A. G. Soares,Sherif I. Elshahawi,Amro Hanora,Eric W. Schmidt,Margo G. Haygood,Janos Posfai,Jack S. Benner,Catherine L. Madinger,John Nove,Brian P. Anton,Kshitiz Chaudhary,Jeremy M. Foster,Alex Holman,Sanjay Kumar,Philip A. Lessard,Yvette A. Luyten,Barton E. Slatko,Nicole Wood,Bo Wu,Max Teplitski,Joseph D. Mougous,Naomi L. Ward,Jonathan A. Eisen,Jonathan H. Badger,Daniel L. Distel +37 more
TL;DR: The results suggest that T. turnerae is likely a facultative intracellular ensosymbiont whose niche presently includes, or recently included, free-living existence.
Journal ArticleDOI
The complex methylome of the human gastric pathogen Helicobacter pylori
Juliane Krebes,Richard D. Morgan,Boyke Bunk,Cathrin Spröer,Khai Luong,Raphael Parusel,Brian P. Anton,Christoph König,Christine Josenhans,Jorg Overmann,Richard J. Roberts,Jonas Korlach,Sebastian Suerbaum +12 more
TL;DR: The comprehensive methylomes of two H. pylori strains are determined at single base resolution using Single Molecule Real-Time (SMRT®) sequencing and revealed novel features of both Type I and Type II R-M systems, including frameshift-mediated changes of sequence specificity and the interaction of one MTase with two alternative specificity subunits resulting in different methylation patterns.