Jeremy M. Foster

TL;DR: It is shown that some of these inserted Wolbachia genes are transcribed within eukaryotic cells lacking endosymbionts, potentially providing a mechanism for acquisition of new genes and functions.

TL;DR: Analysis of this first sequenced endosymbiont genome from a filarial nematode provides insight into endosYmbionT evolution and additionally provides new potential targets for elimination of cutaneous and lymphatic human filarial disease.

TL;DR: In this article, the authors sequenced the ∼90 megabase (Mb) genome of the human filarial parasite Brugia malayi and predicted ∼11,500 protein coding genes in 71 Mb of robustly assembled sequence.

TL;DR: It is shown that an exogenously expressed algal nucleotide triphosphate transporter efficiently imports the triph phosphates of both d5SICS and dNaM into Escherichia coli, and that the endogenous replication machinery uses them to accurately replicate a plasmid containing d5 SICS–dNaM.

TL;DR: The contribution of Wolbachia to inflammatory-mediated pathogenesis and adverse reactions to anti-filarial drugs and the outcome of recent field trials using antibiotics as a promising new tool for the treatment of filarial infection and disease are discussed.