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Bruce L. Miller
Researcher at University of California, San Francisco
Publications - 1296
Citations - 135366
Bruce L. Miller is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 163, co-authored 1153 publications receiving 115975 citations. Previous affiliations of Bruce L. Miller include University of Southern California & National Institutes of Health.
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Journal ArticleDOI
Blood protein predictors of brain amyloid for enrichment in clinical trials
Nicholas J. Ashton,Nicholas J. Ashton,Steven J. Kiddle,John Frederick Graf,Malcolm Ward,Alison L. Baird,Alison L. Baird,Abdul Hye,Abdul Hye,Sarah Westwood,Sarah Westwood,Karyuan Vivian Wong,Richard Dobson,Richard Dobson,Gil D. Rabinovici,Bruce L. Miller,Howard J. Rosen,Andrew S. Torres,Zhanpan Zhang,Lennart Thurfjell,Antonia Covin,Cristina Tan Hehir,David Baker,Chantal Bazenet,Chantal Bazenet,Simon Lovestone,Simon Lovestone +26 more
TL;DR: Blood‐based biomarkers predicting NAB would have great utility for the enrichment of AD clinical trials, including large‐scale prevention trials.
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Cognitive functioning in a mildly to moderately depressed geriatric sample: relationship to chronological age.
TL;DR: Test findings suggest that presence of mild to moderate depression may result in premature "aging" of specific cognitive abilities, but once the seventh decade is reached, cognition in depressed and nondepressed individuals appears to be comparable.
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Damage to left frontal regulatory circuits produces greater positive emotional reactivity in frontotemporal dementia
Virginia E. Sturm,Jennifer S. Yokoyama,Janet A. Eckart,Jessica Zakrzewski,Howard J. Rosen,Bruce L. Miller,William W. Seeley,Robert W. Levenson +7 more
TL;DR: It is argued that selective disruption of left hemisphere emotion regulating systems can impair the ability to suppress positive emotions such as happiness, and left-lateralized fronto-striatal atrophy is selectively associated with happiness dysregulation.
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Visuospatial Functioning in the Primary Progressive Aphasias.
Christa Watson,Katherine L. Possin,I. Elaine Allen,H. Isabel Hubbard,Marita Meyer,Ariane E. Welch,Gil D. Rabinovici,Howard J. Rosen,Katherine P. Rankin,Zachary A. Miller,Miguel A. Santos-Santos,Joel H. Kramer,Bruce L. Miller,Maria Luisa Gorno-Tempini +13 more
TL;DR: This extensive examination of performance on visuospatial tasks in the PPA variants solidifies some previous findings and illuminates the possibility of common mechanisms that underlie both linguistic and non-linguistic deficits in the variants.
Journal ArticleDOI
Metacognition in the behavioral variant of frontotemporal dementia and Alzheimer's disease.
Howard J. Rosen,Oscar Alcantar,Jessica Zakrzewski,Arthur P. Shimamura,John Neuhaus,Bruce L. Miller +5 more
TL;DR: The insensitivity of bvFTD patients to overt feedback may point to unique mechanisms, possibly frontally mediated, that add to their severe lack of self-awareness.