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Bruce L. Miller
Researcher at University of California, San Francisco
Publications - 1296
Citations - 135366
Bruce L. Miller is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 163, co-authored 1153 publications receiving 115975 citations. Previous affiliations of Bruce L. Miller include University of Southern California & National Institutes of Health.
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Journal ArticleDOI
Inheritance of frontotemporal dementia.
TL;DR: Familial FTD is usually inherited in an autosomal dominant pattern, and the initial onset is insidious, often consisting of mood and behavioral changes occurring in presenile years that are often erroneously attributed to other nonneurologic causes.
Journal ArticleDOI
Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases
Giovanni Coppola,Subashchandrabose Chinnathambi,Jason Lee,Beth A. Dombroski,Matt Baker,Alexandra I. Soto-Ortolaza,Suzee E. Lee,Eric Klein,Alden Y. Huang,Renee L. Sears,Jessica Lane,Anna Karydas,Robert O. Kenet,Jacek Biernat,Li-San Wang,Carl W. Cotman,Charles DeCarli,Allan I. Levey,John M. Ringman,Mario F. Mendez,Helena C. Chui,Isabelle Le Ber,Isabelle Le Ber,Alexis Brice,Alexis Brice,Michelle K. Lupton,Elisavet Preza,Simon Lovestone,John Powell,Neill R. Graff-Radford,Ronald C. Petersen,Bradley F. Boeve,Carol F. Lippa,Eileen H. Bigio,Ian R. A. Mackenzie,Elizabeth Finger,Andrew Kertesz,Richard J. Caselli,Marla Gearing,Jorge L. Juncos,Bernardino Ghetti,Salvatore Spina,Yvette Bordelon,Wallace W. Tourtellotte,Matthew P. Frosch,Jean Paul Vonsattel,Chris Zarow,Thomas G. Beach,Roger L. Albin,Andrew P. Lieberman,Virginia M.-Y. Lee,John Q. Trojanowski,Vivianna M. Van Deerlin,Thomas D. Bird,Douglas Galasko,Eliezer Masliah,Charles L. White,Juan C. Troncoso,Didier Hannequin,Adam L. Boxer,Michael D. Geschwind,Satish Kumar,Eva Maria Mandelkow,Zbigniew K. Wszolek,Ryan J. Uitti,Dennis W. Dickson,Jonathan L. Haines,Richard Mayeux,Margaret A. Pericak-Vance,Lindsay A. Farrer,Liana G. Apostolova,Steven E. Arnold,Clinton T. Baldwin,Robert Barber,M. Michael Barmada,Thomas G. Beach,Gary W. Beecham,Duane Beekly,David A. Bennett,Deborah Blacker,James D. Bowen,A. Boxer,James R. Burke,Jacqueline L. Buros,Joseph D. Buxbaum,Nigel J. Cairns,Laura B. Cantwell,Chuanhai Cao,Christopher S. Carlson,Regina M. Carney,Minerva M. Carrasquillo,Steven L. Carroll,David G. Clark,Jason J. Corneveaux,Paul K. Crane,Carlos Cruchaga,Jeffrey L. Cummings,Philip L. De Jager,Philip L. De Jager,Charles C. DeCarli,Steven T. DeKosky,F. Yesim Demirci,Ramon Diaz-Arrastia,Malcolm B. Dick,Ranjan Duara,William G. Ellis,Nilufer Ertekin-Taner,Denis A. Evans,Kelley Faber,Kenneth B. Fallon,Martin R. Farlow,Steven H. Ferris,Tatiana Foroud,Paul Gallins,Mary Ganguli,Daniel H. Geschwind,John R. Gilbert,Sid Gilman,Bruno Giordani,Jonathan D. Glass,Alison Goate,Neil Graff-Radford,Robert C. Green,John H. Growdon,Hakon Hakonarson,Ronald L. Hamilton,John Hardy,Lindy E. Harrell,Elizabeth Head,Lawrence S. Honig,Matthew J. Huentelman,Christine M. Hulette,Bradley T. Hyman,Gail P. Jarvik,Gregory A. Jicha,Lee-Way Jin,Nancy Johnson,Gyungah Jun,M. Ilyas Kamboh,Jason Karlawish,A. Karydas,John S. K. Kauwe,Jeffrey Kaye,Ronald C. Kim,Edward H. Koo,Neil W. Kowall,Patricia L. Kramer,Walter A. Kukull,James J. Lah,Eric B. Larson,Oscar L. Lopez,Kathryn L. Lunetta,Wendy J. Mack,Daniel C. Marson,Eden R. Martin,Frank Martiniuk,Deborah C. Mash,Wayne C. McCormick,Susan M. McCurry,Andrew McDavid,Ann C. McKee,M.-Marsel Mesulam,Bruce L. Miller,Carol A. Miller,Joshua W. Miller,Thomas J. Montine,John C. Morris,Amanda J. Myers,Adam C. Naj,Petra Nowotny,Joseph E. Parisi,Daniel P. Perl,Elaine R. Peskind,Wayne W. Poon,Huntington Potter,Joseph F. Quinn,Ashok Raj,Ruchita Rajbhandary,Murray A. Raskind,Eric M. Reiman,Barry Reisberg,Christiane Reitz,Erik D. Roberson,Ekaterina Rogaeva,Roger N. Rosenberg,Mary Sano,Andrew J. Saykin,Andrew J. Saykin,Julie A. Schneider,Lon S. Schneider,William W. Seeley,Michael L. Shelanski,Michael A. Slifer,Charles D. Smith,Joshua A. Sonnen,Peter St George-Hyslop,Peter St George-Hyslop,Robert S. Stern,Rudolph E. Tanzi,Debby W. Tsuang,Badri N. Vardarajan,Harry V. Vinters,Jean Paul G. Vonsattel,Sandra Weintraub,Kathleen A. Welsh-Bohmer,Jennifer Williamson,Randall L. Woltjer,Steven G. Younkin,Owen A. Ross,Rosa Rademakers,Gerard D. Schellenberg,Eckhard Mandelkow +211 more
TL;DR: These data provide the first genetic evidence and functional studies supporting the role of MAPT p.A152T as a rare risk factor for both FTD-s and AD and the concept that rare variants can increase the risk for relatively common, complex neurodegenerative diseases is suggested.
Journal ArticleDOI
Clinicopathological correlations in behavioural variant frontotemporal dementia.
David C. Perry,Jesse A. Brown,Katherine L. Possin,Samir Datta,Andrew Trujillo,Anneliese Radke,Anneliese Radke,Anna Karydas,John Kornak,Ana C. Sias,Gil D. Rabinovici,Maria Luisa Gorno-Tempini,Adam L. Boxer,Mary De May,Katherine P. Rankin,Virginia E. Sturm,Suzee E. Lee,Brandy R. Matthews,Brandy R. Matthews,Aimee W. Kao,Keith A. Vossel,Keith A. Vossel,Maria Carmela Tartaglia,Maria Carmela Tartaglia,Zachary A. Miller,Sang Won Seo,Sang Won Seo,Manu Sidhu,Stephanie E. Gaus,Alissa L. Nana,Jose Norberto S. Vargas,Ji Hye L. Hwang,Rik Ossenkoppele,Rik Ossenkoppele,Alainna B. Brown,Alainna B. Brown,Eric J. Huang,Giovanni Coppola,Howard J. Rosen,Daniel H. Geschwind,John Q. Trojanowski,Lea T. Grinberg,Joel H. Kramer,Bruce L. Miller,William W. Seeley +44 more
TL;DR: In this paper, the authors explored clinicopathological correlations in a large bvFTD cohort and used a combination of known predictive factors (genetic mutations, motor features, or striking atrophy patterns) and the results of a discriminant function analysis that incorporated clinical, neuroimaging and neuropsychological data.
Journal ArticleDOI
Age effects on atrophy rates of entorhinal cortex and hippocampus.
An Tao Du,Norbert Schuff,Norbert Schuff,Linda L. Chao,Linda L. Chao,John Kornak,John Kornak,William J. Jagust,Joel H. Kramer,Bruce R Reed,Bruce L. Miller,David Norman,Helena C. Chui,Michael W. Weiner +13 more
TL;DR: Age and presence of lacunes should be taken into consideration in imaging studies of CN subjects and AD patients to predict AD progression and assess the response to treatment trials.
Journal ArticleDOI
Neuroimaging in Dementia
TL;DR: The role of imaging in dementia has traditionally been directed at ruling out treatable and reversible etiologies and not to use imaging to better understand the pathophysiology of the different dementias.