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Bruce L. Miller
Researcher at University of California, San Francisco
Publications - 1296
Citations - 135366
Bruce L. Miller is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 163, co-authored 1153 publications receiving 115975 citations. Previous affiliations of Bruce L. Miller include University of Southern California & National Institutes of Health.
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Journal ArticleDOI
Patterns of Cerebral Hypoperfusion in Amnestic and Dysexecutive MCI
Linda L. Chao,Judy Pa,Audrey Duarte,Norbert Schuff,Michael W. Weiner,Joel H. Kramer,Bruce L. Miller,Katie M. Freeman,Julene K. Johnson +8 more
TL;DR: The finding that single-domain MCI patients with prominent deficits in different cognitive domains exhibited different patterns of hypoperfusion relative to controls supports the existence of distinct subgroups of MCI and suggests that cognitive impairment in MCI is related to cerebral hypoperFusion.
Journal ArticleDOI
Diagnosis and Management of Behavioral Variant Frontotemporal Dementia
Peter Pressman,Bruce L. Miller +1 more
TL;DR: Recognizing the various presentations of bvFTD and its histological and genetic subtypes might further diagnosis, treatment, and research, and suggest that functional networks are diminished that might be relevant to empathy and social behavior.
Journal ArticleDOI
What role does the anterior temporal lobe play in sentence-level processing? neural correlates of syntactic processing in semantic variant primary progressive aphasia
Stephen M. Wilson,Andrew T. DeMarco,Maya L. Henry,Benno Gesierich,Miranda Babiak,Maria Luisa Mandelli,Bruce L. Miller,Maria Luisa Gorno-Tempini +7 more
TL;DR: The findings indicate that spared syntactic processing in semantic PPA depends on preserved functionality of structurally intact left frontal regions and moderately atrophic left posterior temporal regions, but no functional reorganization was apparent as a consequence of anterior temporal atrophy and dysfunction.
Journal ArticleDOI
Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans.
Panos Theofilas,Alexander J. Ehrenberg,Austin Nguy,Julia M. Thackrey,Sara Dunlop,Maria B. Mejia,Ana Tereza Di Lorenzo Alho,Renata Elaine Paraizo Leite,Roberta Diehl Rodriguez,Claudia K. Suemoto,Camila F. Nascimento,Marcus Y. Chin,Daniel Medina-Cleghorn,Ana Maria Cuervo,Michelle R. Arkin,William W. Seeley,Bruce L. Miller,Ricardo Nitrini,Carlos Augusto Pasqualucci,Wilson Jacob Filho,Udo Rueb,John Neuhaus,Helmut Heinsen,Lea T. Grinberg,Lea T. Grinberg +24 more
TL;DR: Overall, caspases may be involved in upstream cascades in AD and are associated with higher NFTs and macroautophagy changes correlate with increasing NFT burden from early AD stages.
Journal ArticleDOI
Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study
Cyril Pottier,Xiaolai Zhou,Ralph B. Perkerson,Matthew B. Baker,Gregory D. Jenkins,Daniel J. Serie,Roberta Ghidoni,Luisa Benussi,Giuliano Binetti,Adolfo López de Munain,Adolfo López de Munain,Miren Zulaica,Miren Zulaica,Fermin Moreno,Fermin Moreno,Isabelle Le Ber,Florence Pasquier,Didier Hannequin,Raquel Sánchez-Valle,Anna Antonell,Albert Lladó,Tammee M. Parsons,Nicole A. Finch,Elizabeth Finger,Carol F. Lippa,Edward D. Huey,Manuela Neumann,Manuela Neumann,Peter Heutink,Peter Heutink,Matthis Synofzik,Matthis Synofzik,Carlo Wilke,Carlo Wilke,Robert A. Rissman,Robert A. Rissman,Jarosław Sławek,Emilia J. Sitek,Peter Johannsen,Jorgen E. Nielsen,Yingxue Ren,Marka van Blitterswijk,Mariely DeJesus-Hernandez,Elizabeth Christopher,Melissa E. Murray,Kevin F. Bieniek,Bret M. Evers,Camilla Ferrari,Sara Rollinson,Anna Richardson,Elio Scarpini,Giorgio G. Fumagalli,Giorgio G. Fumagalli,Alessandro Padovani,John Hardy,Parastoo Momeni,Raffaele Ferrari,Francesca Frangipane,Raffaele Maletta,Maria Anfossi,Maura Gallo,Leonard Petrucelli,EunRan Suh,Oscar L. Lopez,Tsz H. Wong,Jeroen van Rooij,Harro Seelaar,Simon Mead,Richard J. Caselli,Eric M. Reiman,Marwan N. Sabbagh,Mads Kjolby,Anders Nykjaer,Anna Karydas,Adam L. Boxer,Lea T. Grinberg,Jordan Grafman,Salvatore Spina,Salvatore Spina,Adrian L. Oblak,M.-Marsel Mesulam,Sandra Weintraub,Changiz Geula,John R. Hodges,Olivier Piguet,William S. Brooks,William S. Brooks,David J. Irwin,John Q. Trojanowski,Edward B. Lee,Keith A. Josephs,Joseph E. Parisi,Nilufer Ertekin-Taner,David S. Knopman,Benedetta Nacmias,Irene Piaceri,Silvia Bagnoli,Sandro Sorbi,Marla Gearing,Jonathan Glass,Thomas G. Beach,Sandra E. Black,Mario Masellis,Ekaterina Rogaeva,Jean-Paul Vonsattel,Lawrence S. Honig,Julia Kofler,Amalia C. Bruni,Julie S. Snowden,David M. A. Mann,Stuart Pickering-Brown,Janine Diehl-Schmid,Juliane Winkelmann,Daniela Galimberti,Caroline Graff,Linn Öijerstedt,Claire Troakes,Safa Al-Sarraj,Safa Al-Sarraj,Carlos Cruchaga,Nigel J. Cairns,Jonathan D. Rohrer,Glenda M. Halliday,John B.J. Kwok,John C. van Swieten,John C. van Swieten,Charles L. White,Bernardino Ghetti,Jill R. Murell,Ian R. Mackenzie,Ging-Yuek Robin Hsiung,Barbara Borroni,Giacomina Rossi,Fabrizio Tagliavini,Zbigniew K. Wszolek,Ronald C. Petersen,Eileen H. Bigio,Murray Grossman,Vivianna M. Van Deerlin,William W. Seeley,Bruce L. Miller,Neill R. Graff-Radford,Bradley F. Boeve,Dennis W. Dickson,Joanna M. Biernacka,Rosa Rademakers +145 more
TL;DR: In this paper, a meta-analysis was conducted to identify potential genetic modifiers of disease onset and disease risk in frontotemporal lobar degeneration (FTLD) carriers.