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Bruce L. Miller

Researcher at University of California, San Francisco

Publications -  1296
Citations -  135366

Bruce L. Miller is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 163, co-authored 1153 publications receiving 115975 citations. Previous affiliations of Bruce L. Miller include University of Southern California & National Institutes of Health.

Papers
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Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Cyril Pottier, +119 more
TL;DR: A possible role for genes functioning within the TBK1-related immune pathway (e.g., DHX58, TRIM21, IRF7) in the genetic etiology of FTLD-TDP is discovered and strongly implicates the immune pathway in FTLD/TDP pathogenesis.
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CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP.

TL;DR: The inverse correlation of p-tau with disease severity suggests a potentially different mechanism of tau pathology in PSP as compared to Alzheimer disease.
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Deconstructing empathy: Neuroanatomical dissociations between affect sharing and prosocial motivation using a patient lesion model.

TL;DR: It is found that the affect sharing component uniquely correlated with volume in right>left medial and lateral temporal lobe structures, including the amygdala and insula, that support emotion recognition, emotion generation, and emotional awareness.
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Cognitive and Behavioral Challenges in Caring for Patients with Frontotemporal dementia and Amyotrophic Lateral Sclerosis

TL;DR: This paper provides a guide for healthcare providers caring for patients with FTD-ALS exhibiting behavioral, cognitive, and emotional symptoms and strategies are suggested to help minimize the impact of negative symptoms.
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Fluent versus nonfluent primary progressive aphasia: a comparison of clinical and functional neuroimaging features.

TL;DR: Fluent and nonfluent forms of PPA are clinically distinguishable by letter fluency, single word comprehension, object naming, and types of paraphasic errors, and there is a large amount of overlap between dysfunctional anatomic regions associated with these syndromes.