B
Bruno Iles
Researcher at Federal University of Piauí
Publications - 10
Citations - 107
Bruno Iles is an academic researcher from Federal University of Piauí. The author has contributed to research in topics: Medicine & Nanocarriers. The author has an hindex of 5, co-authored 7 publications receiving 51 citations.
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Journal ArticleDOI
Evaluation of antitumor potential of cashew gum extracted from Anacardium occidentale Linn.
A.B. Barros,A.F. Moura,Durcilene Alves da Silva,Taiane Maria de Oliveira,Francisco Stefânio Barreto,Wesley Lyeverton Correia Ribeiro,Ana Paula Negreiros Nunes Alves,Ana Carolina Justino de Araújo,M.O. Moraes Filho,Bruno Iles,Jand Venes R. Medeiros,J.D.B. Marinho-Filho +11 more
TL;DR: It is suggested that this polymer can assist in the anticancer activity and/or decrease the side effects of standard drugs used in treatment of cancer.
Journal ArticleDOI
Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activation in Microglia and Hippocampal Neurons
Nayara A. Sousa,Guilherme Antônio Lopes de Oliveira,Ana Patrícia de Oliveira,André Luis Fernandes Lopes,Bruno Iles,Kerolayne M. Nogueira,Thiago S.L. Araújo,Luan Kelves Miranda de Souza,Alyne Rodrigues de Araújo,Joilson Ramos-Jesus,Alexandra Plácido,Alexandra Plácido,Constança Pais do Amaral,Yuri D. M. Campelo,Eder Alves Barbosa,Camila C. Portugal,Renato Socodato,Andrea Lobo,João B. Relvas,Marcelo P. Bemquerer,Peter Eaton,Peter Eaton,José Roberto S. A. Leite,Jand Venes R. Medeiros +23 more
TL;DR: Functional properties of peptides obtained from the cutaneous secretions of the amphibian, Leptodactylus vastus, suggest possible to neuromodulatory therapeutic applications and low cytotoxicity towards erythrocytes.
Journal ArticleDOI
Antifungal and anti-inflammatory potential of eschweilenol C-rich fraction derived from Terminalia fagifolia Mart.
Alyne Rodrigues de Araújo,Bruno Iles,Kerolayne M. Nogueira,Jhones do Nascimento Dias,Alexandra Plácido,Artur Rodrigues,Patrícia Albuquerque,Ildinete Silva-Pereira,Renato Socodatto,Camila C. Portugal,João B. Relvas,Leiz Maria Costa Véras,Filipe C. D. A. Lima,Augusto Batagin-Neto,Jand Venes R. Medeiros,Paulo Humberto Moreira Nunes,Peter Eaton,José Roberto S. A. Leite,José Roberto S. A. Leite +18 more
TL;DR: Eschweilenol C was identified as the major constituent of the aqueous fraction of the ethanolic extract of T. fagifolia and demonstrated the ability to inhibit NF-κB after induction with lipopolysaccharide and an excellent antioxidant potential.
Journal ArticleDOI
Recent trends in praziquantel nanoformulations for helminthiasis treatment
TL;DR: This review focuses on the various types of nanomaterials (polymeric, lipidic, inorganic nanoparticles, and nanocrystals) which have been recently used to improve PZQ therapy and recent advances in PZZ nanoformulations, developed to overcome the barriers of the conventional drug.
Journal ArticleDOI
Carvacryl acetate, a novel semisynthetic monoterpene ester, binds to the TRPA1 receptor and is effective in attenuating irinotecan-induced intestinal mucositis in mice.
Elenice Monte Alvarenga,Nayara A. Sousa,Simone de Araújo,José Lopes Pereira Júnior,Alyne Rodrigues de Araújo,Bruno Iles,Dvison M. Pacífico,Gerly Anne de Castro Brito,Emmanuel P. Souza,Damião Pergentino de Sousa,Jand Venes R. Medeiros +10 more
TL;DR: Whether carvacryl acetate acts as a TRPA1 receptor agonist and its effects against irinotecan (CPT‐11) induced intestinal mucositis in mice is investigated.