C
C. Gooden
Researcher at National Institutes of Health
Publications - 6
Citations - 2101
C. Gooden is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene expression profiling & Complementary DNA. The author has an hindex of 3, co-authored 6 publications receiving 2045 citations.
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Journal ArticleDOI
Molecular classification of cutaneous malignant melanoma by gene expression profiling
M. Bittner,Paul S. Meltzer,Yi Chen,Yong-hui Jiang,E. A. Seftor,Mary J.C. Hendrix,Michael D. Radmacher,Richard M. Simon,Zohar Yakhini,Amir Ben-Dor,Amir Ben-Dor,Nick Sampas,Edward R. Dougherty,Ena Wang,Francesco M. Marincola,C. Gooden,John Lueders,Arthur A. Glatfelter,P.C.A. Pollock,John D. Carpten,E. Gillanders,D. Leja,K. Dietrich,Christian Beaudry,Michael E. Berens,David S. Alberts,Vernon K. Sondak,Nicholas K. Hayward,J.M. Trent +28 more
TL;DR: Many genes underlying the classification of this subset of melanomas are differentially regulated in invasive melanomas that form primitive tubular networks in vitro, a feature of some highly aggressive metastatic melanomas.
Molecular classification of cutaneous malignant melanoma by gene expression profiling
M. Bittner,P. Meltzer,Yi Chen,Yong-hui Jiang,E. A. Seftor,Mary J.C. Hendrix,Michael D. Radmacher,Richard M. Simon,Zohar Yakhini,Amir Ben-Dor,Nick Sampas,Edward R. Dougherty,E. Wang,Francesco M. Marincola,C. Gooden,John Lueders,Arthur A. Glatfelter,Pamela M. Pollock,John D. Carpten,E. Gillanders,D. Leja,K. Dietrich,Christian Beaudry,Michael E. Berens,David S. Alberts,Vernon K. Sondak +25 more
TL;DR: In this paper, a subset of melanomas identified by mathematical analysis of gene expression in a series of samples was identified by identifying the genes underlying the classification of this subset are differentially regulated in invasive melanomas.
Journal ArticleDOI
Profiling human gene expression with cDNA microarrays.
TL;DR: In this article, the authors describe methods that allow cDNA clones representing the 3' ends of many human genes to be used as hybridization detectors in a highly parallel assay of gene expression.
Journal ArticleDOI
Molecular pathophysiologic hints into Niemann-Pick Type C disease using cDNA microarray technology
Dietrich A. Stephan,David O. Azorsa,David Duggan,Lindsay Malechek,C. Gooden,M. Bittner,Yi Chen,Paul S. Meltzer,J.M. Trent,Melissa A. Ashlock +9 more
TL;DR: Molecular pathophysiologic hints into Niemann-Pick Type C disease using cDNA microarray technology are provided and further research is needed to understand the mechanisms behind the disease.
Journal ArticleDOI
Profiling human gene expression with cDNA microarrays.
TL;DR: This unit describes methods that allow cDNA clones representing the 3 ends of many human genes to be used as hybridization detectors in a highly parallel assay of gene expression.