M
Mary J.C. Hendrix
Researcher at Northwestern University
Publications - 293
Citations - 27970
Mary J.C. Hendrix is an academic researcher from Northwestern University. The author has contributed to research in topics: Melanoma & Vasculogenic mimicry. The author has an hindex of 88, co-authored 291 publications receiving 26692 citations. Previous affiliations of Mary J.C. Hendrix include Veterans Health Administration & Fox Chase Cancer Center.
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Journal ArticleDOI
Molecular classification of cutaneous malignant melanoma by gene expression profiling
M. Bittner,Paul S. Meltzer,Yi Chen,Yong-hui Jiang,E. A. Seftor,Mary J.C. Hendrix,Michael D. Radmacher,Richard M. Simon,Zohar Yakhini,Amir Ben-Dor,Amir Ben-Dor,Nick Sampas,Edward R. Dougherty,Ena Wang,Francesco M. Marincola,C. Gooden,John Lueders,Arthur A. Glatfelter,P.C.A. Pollock,John D. Carpten,E. Gillanders,D. Leja,K. Dietrich,Christian Beaudry,Michael E. Berens,David S. Alberts,Vernon K. Sondak,Nicholas K. Hayward,J.M. Trent +28 more
TL;DR: Many genes underlying the classification of this subset of melanomas are differentially regulated in invasive melanomas that form primitive tubular networks in vitro, a feature of some highly aggressive metastatic melanomas.
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Vascular Channel Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry
Andrew J. Maniotis,Robert Folberg,Angela R. Hess,Elisabeth A. Seftor,Lynn M. G. Gardner,Jacob Pe'er,Jeffrey M. Trent,Paul S. Meltzer,Mary J.C. Hendrix +8 more
TL;DR: It is suggested that aggressive melanoma cells may generate vascular channels that facilitate tumor perfusion independent of tumor angiogenesis, providing a biomechanical explanation for the generation of microvessels in vitro.
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Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells
Zhiqiang Zou,Anthony Anisowicz,Mary J.C. Hendrix,Ann D. Thor,Mark Joseph Neveu,Shijie Sheng,Kristina Rafidi,Elisabeth A. Seftor,Ruth Sager +8 more
TL;DR: Results support the hypothesis that maspin functions as a tumor suppressor and reduce the cells' ability to induce tumors and metastasize in nude mice and to invade through a basement membrane matrix in vitro.
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Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma
TL;DR: The gene expression profile of aggressive cutaneous and uveal melanoma cells resembles that of an undifferentiated, embryonic-like cell as mentioned in this paper, which has been termed "vasculogenic mimicry".
Journal ArticleDOI
Vasculogenic Mimicry and Tumor Angiogenesis
TL;DR: The unique patterning characteristic of vasculogenic mimicry provides an opportunity to design noninvasive imaging techniques to detect highly aggressive neoplasms and their metastases.