C
Carina Conzelmann
Researcher at University of Ulm
Publications - 46
Citations - 1730
Carina Conzelmann is an academic researcher from University of Ulm. The author has contributed to research in topics: Medicine & Innate immune system. The author has an hindex of 14, co-authored 36 publications receiving 794 citations.
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Journal ArticleDOI
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas.
Janis A. Müller,Rüdiger Groß,Carina Conzelmann,Jana Krüger,Uta Merle,Johannes Steinhart,Tatjana Weil,Lennart Koepke,Caterina Prelli Bozzo,Clarissa Read,Giorgio Fois,Tim Eiseler,Julia Gehrmann,Joanne van Vuuren,Isabel M Wessbecher,Manfred Frick,Ivan G. Costa,Markus Breunig,Beate Grüner,Lynn Peters,Michael Schuster,Stefan Liebau,Thomas Seufferlein,Steffen Stenger,Albrecht Stenzinger,Patrick E. MacDonald,Frank Kirchhoff,Konstantin M. J. Sparrer,Paul Walther,Heiko Lickert,Thomas F. E. Barth,Martin Wagner,Jan Münch,Sandra Heller,Alexander Kleger +34 more
TL;DR: In this paper, the authors identify the human pancreas as a target of SARS-CoV-2 infection and suggest that β-cell infection could contribute to the metabolic dysregulation observed in patients with COVID-19.
Journal ArticleDOI
Detection of SARS-CoV-2 in human breastmilk.
Rüdiger Groß,Carina Conzelmann,Janis A. Müller,Steffen Stenger,Karin Steinhart,Frank Kirchhoff,Jan Münch +6 more
TL;DR: In this article, the authors examined milk from two nursing mothers infected with SARS-CoV-2 and found that SARS RNA was detected in milk samples from Mother 2 for 4 consecutive days.
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Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities.
Manuel Hayn,Maximilian Hirschenberger,Lennart Koepke,Rayhane Nchioua,Jan Hendrik Straub,Susanne Klute,Victoria Hunszinger,Fabian Zech,Caterina Prelli Bozzo,Wasim Aftab,Maria H Christensen,Carina Conzelmann,Janis A. Müller,Smitha Srinivasachar Badarinarayan,Christina M. Stürzel,Ignasi Forné,Steffen Stenger,Karl-Klaus Conzelmann,Jan Münch,Florian I. Schmidt,Daniel Sauter,Axel Imhof,Frank Kirchhoff,Konstantin Maria Johannes Sparrer +23 more
TL;DR: In this article, the authors systematically analyzed the impact of SARS-CoV-2 proteins on interferon (IFN) responses and autophagy, and they showed that SARS co-virus 2 proteins synergize to counteract anti-viral immune responses.
Journal ArticleDOI
Erratum to: Virucidal Efficacy of Different Oral Rinses Against Severe Acute Respiratory Syndrome Coronavirus 2
Toni Luise Meister,Yannick Brüggemann,Daniel Todt,Carina Conzelmann,Janis A. Müller,Rüdiger Groß,Jan Münch,Adalbert Krawczyk,Jörg Steinmann,Jochen Steinmann,Stephanie Pfaender,Eike Steinmann +11 more
TL;DR: Several formulations with significant Sars-CoV-2 inactivating properties in vitro support the idea that oral rinsing might reduce the viral load of saliva and could thus lower the transmission of SARS-Cov-2.
Journal ArticleDOI
SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans.
Rayhane Nchioua,Dorota Kmiec,Dorota Kmiec,Janis A. Müller,Carina Conzelmann,Rüdiger Groß,Chad M. Swanson,Stuart J. D. Neil,Steffen Stenger,Daniel Sauter,Jan Münch,Konstantin M. J. Sparrer,Frank Kirchhoff +12 more
TL;DR: The results show that ZAP is an important effector of the innate response against SARS-CoV-2, although this pandemic pathogen emerged from zoonosis of a coronavirus that was preadapted to the low-CpG environment in humans.