C
Carlos U. Corvera
Researcher at University of California, San Francisco
Publications - 108
Citations - 6903
Carlos U. Corvera is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 28, co-authored 77 publications receiving 5686 citations. Previous affiliations of Carlos U. Corvera include Veterans Health Administration & United States Department of Veterans Affairs.
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Journal ArticleDOI
Improvement in Perioperative Outcome After Hepatic Resection: Analysis of 1,803 Consecutive Cases Over the Past Decade
William R. Jarnagin,Mithat Gonen,Yuman Fong,Ronald P. DeMatteo,Leah Ben-Porat,Sarah A Little,Carlos U. Corvera,Sharon M. Weber,Leslie H. Blumgart +8 more
TL;DR: Assessment of the nature of changes in the field of hepatic resectional surgery and their impact on perioperative outcome to establish a baseline for this type of surgery.
Journal ArticleDOI
Proteinase-activated receptors: novel mechanisms of signaling by serine proteases
TL;DR: Because the cleaved receptor is physically coupled to its agonist, efficient mechanisms exist to terminate signaling and prevent uncontrolled stimulation, including cleavage of the tethered ligand, receptor phosphorylation and uncoupling from G proteins, and endocytosis and lysosomal degradation of activated receptors.
Journal ArticleDOI
Esophageal and Esophagogastric Junction Cancers, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology.
Jaffer A. Ajani,Thomas A. D'Amico,David J. Bentrem,Joseph Chao,Carlos U. Corvera,Prajnan Das,Crystal S. Denlinger,Peter C. Enzinger,Paul T. Fanta,Farhood Farjah,Hans Gerdes,Michael Gibson,Robert E. Glasgow,James A. Hayman,Steven N. Hochwald,Wayne L. Hofstetter,David H. Ilson,Dawn E. Jaroszewski,Kimberly L. Johung,Rajesh N. Keswani,Lawrence Kleinberg,Stephen Leong,Quan P. Ly,Kristina A. Matkowskyj,Michael McNamara,Mary F. Mulcahy,Ravi Kumar Paluri,Haeseong Park,Kyle A. Perry,Jose M. Pimiento,George A. Poultsides,Robert E. Roses,Vivian E. Strong,Georgia L. Wiesner,Christopher G. Willett,Cameron D. Wright,Nicole R. McMillian,Lenora A. Pluchino +37 more
TL;DR: This selection from the NCCN Guidelines for Esophageal and Esophagogastric Junction Cancers focuses on recommendations for the management of locally advanced and metastatic adenocarcinoma of the esophagus and EGJ.
Journal ArticleDOI
Gastric Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
Jaffer A. Ajani,Thomas A. D'Amico,David J. Bentrem,Joseph Chao,David Cooke,Carlos U. Corvera,Prajnan Das,Peter C. Enzinger,Thomas Enzler,Paul T. Fanta,Farhood Farjah,Hans Gerdes,C. Michael Gibson,Steven N. Hochwald,Wayne L. Hofstetter,David H. Ilson,Rajesh N. Keswani,Sunnie Kim,Lawrence Kleinberg,Samuel J. Klempner,Jill Lacy,Quan P. Ly,Kristina A. Matkowskyj,Michael McNamara,Mary F. Mulcahy,Darryl Alan Outlaw,Haeseong Park,Kyle A. Perry,Jose M. Pimiento,George A. Poultsides,Scott I. Reznik,Robert Ross,Vivian E. Strong,Stacey Su,Hanlin L. Wang,Georgia L. Wiesner,Christopher G. Willett,Danny Yakoub,Harry H. Yoon,Nicole R. McMillian,Lenora A. Pluchino +40 more
TL;DR: Palliative management, which may include systemic therapy, chemoradiation, and/or best supportive care, is recommended for all patients with unresectable or metastatic cancer.
Journal ArticleDOI
The TGR5 receptor mediates bile acid–induced itch and analgesia
Farzad Alemi,Edwin Kwon,Daniel P. Poole,Tina Marie Lieu,Victoria Lyo,Fiore Cattaruzza,Ferda Cevikbas,Martin Steinhoff,Romina Nassini,Serena Materazzi,Raquel Guerrero-Alba,Eduardo E. Valdez-Morales,Graeme S. Cottrell,Kristina Schoonjans,Pierangelo Geppetti,Stephen J. Vanner,Nigel W. Bunnett,Carlos U. Corvera +17 more
TL;DR: Bile acids activate TGR5 on sensory nerves, stimulating the release of neuropeptides in the spinal cord that transmit itch and analgesia, which could contribute to pruritus and painless jaundice that occur during cholestatic liver diseases.