C
Carolyn Williams
Researcher at Imperial College London
Publications - 16
Citations - 3665
Carolyn Williams is an academic researcher from Imperial College London. The author has contributed to research in topics: Cystic fibrosis & ΔF508. The author has an hindex of 11, co-authored 15 publications receiving 3495 citations. Previous affiliations of Carolyn Williams include Centre national de la recherche scientifique.
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Journal Article
Male circumcision for HIV prevention in young men in Kisumu, Kenya : a randomised controlled trial. Commentary
Marie-Louise Newell,Till Bärnighausen,Robert C. Bailey,Stephen Moses,Corette B. Parker,Kawango Agot,Ian Maclean,John N. Krieger,Carolyn Williams,Richard T. Campbell,Jeckoniah O. Ndinya-Achola +10 more
TL;DR: Male circumcision significantly reduces the risk of HIV acquisition in young men in Africa and should be integrated with other HIV preventive interventions and provided as expeditiously as possible.
Journal Article
Male circumcision for HIV prevention in men in Rakai, Uganda : a randomised trial. Commentary
Marie-Louise Newell,Till Bärnighausen,Ronald H. Gray,Godfrey Kigozi,David Serwadda,Frederick Makumbi,Stephen Watya,Fred Nalugoda,Noah Kiwanuka,Lawrence H. Moulton,Mohammad A Chaudhary,Michael Z. Chen,Nelson K. Sewankambo,Fred Wabwire-Mangen,Melanie C. Bacon,Carolyn Williams,Pius Opendi,Steven J. Reynolds,Oliver Laeyendecker,Thomas C. Quinn,Maria J. Wawer +20 more
TL;DR: In this article, the effect of male circumcision on HIV incidence in men was investigated on a randomized trial in rural Rakai district, Uganda, where 4996 uncircumcised, HIV-negative men aged 15-49 years who agreed to HIV testing and counselling were enrolled in this randomised trial.
Journal ArticleDOI
Genotype analysis for ΔF508, G551D and R553X mutations in children and young adults with cystic fibrosis with and without chronic liver disease
Ann Duthie,Derek G. Doherty,Carolyn Williams,Robert Scott-Jupp,J. O. Warner,M. Stuart Tanner,Robert Williamson,Alex P. Mowat +7 more
TL;DR: A familial concordance for clinical liver disease of 20% in this study, compared with a reported prevalence of 4.7%, suggests that genes outside the cystic fibrosis locus and/or environmental factors are involved in the pathogenesis of liver disease in cystic Fibrosis.
Journal ArticleDOI
Incidence and expression of the N1303K mutation of the cystic fibrosis (CFTR) gene
L. Osborne,George Santis,Martin Schwarz,Katherine W. Klinger,Thilo Dörk,I. McIntosh,Marianne Schwartz,V. Nunes,Milan Macek,Jochen Reiss,W. E. Highsmith,Robert C. McMahon,Giuseppe Novelli,N. Malik,J. Bürger,Maria Anvret,A. Wallace,Carolyn Williams,Christopher G. Mathew,Rima Rozen,Colin A. Graham,Paolo Gasparini,J. Bal,Jj. Cassiman,A. Balassopoulou,L. Davidow,Salmo Raskin,Luba Kalaydjieva,Batsheva Kerem,S. Richards,Brigitte Simon-Bouy,M. Super,U. Wulbrand,M. Keston,Xavier Estivill,V. Vavrova,K. J. Friedman,David E. Barton,Bruno Dallapiccola,Manfred Stuhrmann,F. Beards,Alison J. M. Hill,Pier Franco Pignatti,Harry Cuppens,Dora Angelicheva,Burkhard Tümmler,David J. H. Brock,Teresa Casals,Joerg Schmidtke,Alex Magee,A. Bonizzato,C. De Boeck,A. Kuffardjieva,M. Hodson,Richard A. Knight +54 more
TL;DR: The N1303K mutation is classified as a “severe” mutation with respect to the pancreas, but can find no correlation between this mutation, in either the homozygous or heterozygous state, and the severity of lung disease.