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Cédric Blanpain
Researcher at Université libre de Bruxelles
Publications - 158
Citations - 29641
Cédric Blanpain is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Stem cell & Cellular differentiation. The author has an hindex of 73, co-authored 149 publications receiving 24527 citations. Previous affiliations of Cédric Blanpain include French Alternative Energies and Atomic Energy Commission & Howard Hughes Medical Institute.
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Journal ArticleDOI
Defining the epithelial stem cell niche in skin.
Tudorita Tumbar,Géraldine Guasch,Valentina Greco,Cédric Blanpain,William E. Lowry,Michael Rendl,Elaine Fuchs +6 more
TL;DR: It is found that these cells rarely divide within their niche but change properties abruptly when stimulated to exit, and their transcriptional profile is determined, which, when compared to progeny and other SCs, defines the niche.
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The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54.
Masato Kotani,Michel Detheux,Ann Vandenbogaerde,David Communi,Jean-Marie Vanderwinden,Emmanuel Le Poul,Stéphane Brézillon,Richard Tyldesley,Nathalie Suarez-Huerta,Fabrice Vandeput,Cédric Blanpain,Serge N. Schiffmann,Gilbert Vassart,Marc Parmentier +13 more
TL;DR: Stimulation of oxytocin secretion after kisspeptin administration to rats confirmed this hypothesis that human GPR54 was highly expressed in placenta, pituitary, pancreas, and spinal cord, suggesting a role in the regulation of endocrine function.
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EMT Transition States during Tumor Progression and Metastasis.
TL;DR: The role of the transcriptional and epigenetic landscapes, gene regulatory network and their surrounding niche in controlling the transition through the different EMT states in cancer is summarized.
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Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche.
TL;DR: It is suggested that the niche microenvironment imposes intrinsic "stemness" features without restricting the establishment of epithelial polarity and changes in gene expression.
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Epidermal homeostasis: a balancing act of stem cells in the skin.
Cédric Blanpain,Elaine Fuchs +1 more
TL;DR: Interestingly, the basic mechanisms and signalling pathways that orchestrate epithelial morphogenesis in the skin are reused during adult life to regulate skin homeostasis.