C
Chan Young Park
Researcher at Ulsan National Institute of Science and Technology
Publications - 37
Citations - 4581
Chan Young Park is an academic researcher from Ulsan National Institute of Science and Technology. The author has contributed to research in topics: Calmodulin & ORAI1. The author has an hindex of 22, co-authored 32 publications receiving 4209 citations. Previous affiliations of Chan Young Park include Gyeongsang National University & Stanford University.
Papers
More filters
Journal ArticleDOI
STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1
Chan Young Park,Paul Hoover,Franklin M. Mullins,Priti Bachhawat,Elizabeth D. Covington,Stefan Raunser,Thomas Walz,Thomas Walz,K. Christopher Garcia,Ricardo E. Dolmetsch,Richard S. Lewis +10 more
TL;DR: These studies establish a molecular mechanism for store-operated Ca(2+) entry in which the direct binding of STIM1 to Orai1 drives the accumulation and the activation of CRAC channels at ER-PM junctions.
Journal ArticleDOI
Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis
Cagla Eroglu,Cagla Eroglu,Nicola J. Allen,Michael W. Susman,Nancy A. O'Rourke,Chan Young Park,Engin Özkan,Chandrani Chakraborty,Sara B. Mulinyawe,Douglas S. Annis,Andrew D. Huberman,Eric M. Green,Jack Lawler,Ricardo E. Dolmetsch,K. Christopher Garcia,Stephen J. Smith,Z. David Luo,Arnon Rosenthal,Deane F. Mosher,Ben A. Barres +19 more
TL;DR: The neuronal thrombospondin receptor involved in CNS synapse formation is identified as alpha2delta-1, the receptor for the anti-epileptic and analgesic drug gabapentin and suggested that gapapentin may function therapeutically by blocking new synapses formation.
Gabapentin Receptor alpha 2 delta-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis
Cagla Eroglu,Nicola J. Allen,Michael W. Susman,Nancy A. O'Rourke,Chan Young Park,Engin Oezkan,Chandrani Chakraborty,Sara B. Mulinyawe,Douglas S. Annis,Andrew D. Huberman,Eric M. Green,Jack Lawler,Ricardo E. Dolmetsch,K. Christopher Garcia,Stephen J. Smith,Z. David Luo,Arnon Rosenthal,Deane F. Mosher,Ben A. Barres +18 more
Journal ArticleDOI
Pathogen- and NaCl-Induced Expression of the SCaM-4 Promoter Is Mediated in Part by a GT-1 Box That Interacts with a GT-1-Like Transcription Factor
Hyeong Cheol Park,Man Lyang Kim,Yun Hwan Kang,Joo Mi Jeon,Jae Hyuk Yoo,Min Chul Kim,Chan Young Park,Jae Cheol Jeong,Byeong Cheol Moon,Ju Huck Lee,Hae Won Yoon,Sung-Ho Lee,Woo Sik Chung,Chae Oh Lim,Sang Yeol Lee,Jong Chan Hong,Moo Je Cho +16 more
TL;DR: Results suggest that an interaction between aGT-1 cis-element and a GT-1-like transcription factor plays a role in pathogen- and salt-induced SCaM-4 gene expression in both soybean and Arabidopsis.
Journal ArticleDOI
The CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels
TL;DR: It is found that STIM1 (stromal interaction molecule 1), the main activator of store-operated Ca2+ channels, directly suppresses depolarization-induced opening of the voltage-gated Ca 2+ channel CaV1.2.