C
Changsoo Paul Kang
Researcher at KAIST
Publications - 9
Citations - 906
Changsoo Paul Kang is an academic researcher from KAIST. The author has contributed to research in topics: Genotype & Single-nucleotide polymorphism. The author has an hindex of 8, co-authored 9 publications receiving 878 citations.
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Journal ArticleDOI
A functional variant in FCRL3 , encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities
Yuta Kochi,Ryo Yamada,Akari Suzuki,John B. Harley,John B. Harley,John B. Harley,Senji Shirasawa,Tetsuji Sawada,Sang Cheol Bae,Shinya Tokuhiro,Xiaotian Chang,Akihiro Sekine,Atsushi Takahashi,Tatsuhiko Tsunoda,Yozo Ohnishi,Kenneth M. Kaufman,Kenneth M. Kaufman,Kenneth M. Kaufman,Changsoo Paul Kang,Changwon Kang,Shigeru Otsubo,Wako Yumura,Akio Mimori,Takao Koike,Yusuke Nakamura,Takehiko Sasazuki,Kazuhiko Yamamoto +26 more
TL;DR: A SNP in the promoter region of FCRL3, a member of the Fc receptor-like family, that is associated with susceptibility to rheumatoid arthritis is identified and this polymorphism alters the binding affinity of nuclear factor-κB and regulatesFCRL3 expression.
Journal ArticleDOI
A functional haplotype of the PADI4 gene associated with increased rheumatoid arthritis susceptibility in Koreans
TL;DR: The association of PADI4 with RA may depend on genetic heterogeneity between Asians and Europeans, as indicated by the genotypic associations sustained among individuals who did not carry any SE alleles, except in the case of padi4_104.
Journal ArticleDOI
The influence of a polymorphism at position −857 of the tumour necrosis factor α gene on clinical response to etanercept therapy in rheumatoid arthritis
TL;DR: In this paper, single-nucleotide polymorphisms (SNPs) within the target genes TNFA and LTA are associated with clinical responses to etanercept therapy in RA patients.
Journal ArticleDOI
Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk
Kyoung-Mu Lee,Ji Yeob Choi,Changwon Kang,Changsoo Paul Kang,Sue Kyung Park,Hyunmi Cho,Dae Yeon Cho,Keun-Young Yoo,Dong Young Noh,Sei Hyun Ahn,Chung Gyu Park,Qingyi Wei,Daehee Kang +12 more
TL;DR: The findings suggest that genetic polymorphisms of RAD52, ERCC1, and hMLH1 may be associated with breast cancer risk in Korean women.
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Association of anti-cyclic citrullinated peptide antibody levels with PADI4 haplotypes in early rheumatoid arthritis and with shared epitope alleles in very late rheumatoid arthritis.
TL;DR: The P ADI4 RA risk haplotype is associated with increased anti-CCP levels in RA patients with disease of short duration, and PADI4 may play a role in early RA, suggesting that SE alleles play a roles in very late RA.