A
Akari Suzuki
Researcher at Tokyo University of Foreign Studies
Publications - 11
Citations - 1086
Akari Suzuki is an academic researcher from Tokyo University of Foreign Studies. The author has contributed to research in topics: Arthritis & Citrullination. The author has an hindex of 10, co-authored 11 publications receiving 1019 citations.
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Journal ArticleDOI
A functional variant in FCRL3 , encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities
Yuta Kochi,Ryo Yamada,Akari Suzuki,John B. Harley,John B. Harley,John B. Harley,Senji Shirasawa,Tetsuji Sawada,Sang Cheol Bae,Shinya Tokuhiro,Xiaotian Chang,Akihiro Sekine,Atsushi Takahashi,Tatsuhiko Tsunoda,Yozo Ohnishi,Kenneth M. Kaufman,Kenneth M. Kaufman,Kenneth M. Kaufman,Changsoo Paul Kang,Changwon Kang,Shigeru Otsubo,Wako Yumura,Akio Mimori,Takao Koike,Yusuke Nakamura,Takehiko Sasazuki,Kazuhiko Yamamoto +26 more
TL;DR: A SNP in the promoter region of FCRL3, a member of the Fc receptor-like family, that is associated with susceptibility to rheumatoid arthritis is identified and this polymorphism alters the binding affinity of nuclear factor-κB and regulatesFCRL3 expression.
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Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis
Xiaotian Chang,Ryo Yamada,Akari Suzuki,Tetsuji Sawada,Shinichi Yoshino,Shinya Tokuhiro,Kazuhiko Yamamoto +6 more
TL;DR: The results showed that PADI4 is mainly distributed in cells of various haematopoietic lineages and expressed at high levels in the inflamed RA synovium and the notion that citrullinated fibrin is a potential antigen of RA autoimmunity is supported.
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Citrullination of fibronectin in rheumatoid arthritis synovial tissue
TL;DR: The results suggest that the citrullination of Fn is a specific event for RA synovium, although others have detectedcitrullinated total proteins in inflamed synovial tissue of RA and non-RA patients.
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Citrullinated fibrinogen detected as a soluble citrullinated autoantigen in rheumatoid arthritis synovial fluids.
Yasunobu Takizawa,Akari Suzuki,Tetsuji Sawada,Mizuko Ohsaka,Tetsufumi Inoue,Ryo Yamada,Kazuhiko Yamamoto +6 more
TL;DR: In this paper, the presence of citrullinated fibrinogen (cFBG) in the plasma or synovial fluid of patients with RA and control patients, and their relationship with serum markers for RA if it is present was investigated.
Journal ArticleDOI
Anti-citrullinated collagen type I antibody is a target of autoimmunity in rheumatoid arthritis.
Akari Suzuki,Ryo Yamada,Miyako Ohtake-Yamanaka,Yuko Okazaki,Tetsuji Sawada,Kazuhiko Yamamoto +5 more
TL;DR: It is concluded that huCI is a novel substrate protein of PADIs and that citrullinated hu CI is a candidate autoantigen of RA.