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Shohko Kunimoto
Researcher at Nagoya University
Publications - 19
Citations - 640
Shohko Kunimoto is an academic researcher from Nagoya University. The author has contributed to research in topics: Genome-wide association study & Copy-number variation. The author has an hindex of 10, co-authored 19 publications receiving 450 citations.
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Journal ArticleDOI
Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights
Itaru Kushima,Branko Aleksic,Masahiro Nakatochi,Teppei Shimamura,Takashi Okada,Yota Uno,Yota Uno,Mako Morikawa,Kanako Ishizuka,Tomoko Shiino,Hiroki Kimura,Yuko Arioka,Akira Yoshimi,Yuto Takasaki,Yanjie Yu,Yukako Nakamura,Maeri Yamamoto,Tetsuya Iidaka,Shuji Iritani,Toshiya Inada,Nanayo Ogawa,Emiko Shishido,Youta Torii,Naoko Kawano,Yutaka Omura,Toru Yoshikawa,Tokio Uchiyama,Toshimichi Yamamoto,Masashi Ikeda,Ryota Hashimoto,Hidenaga Yamamori,Yuka Yasuda,Toshiyuki Someya,Yuichiro Watanabe,Jun Egawa,Ayako Nunokawa,Masanari Itokawa,Makoto Arai,Mitsuhiro Miyashita,Akiko Kobori,Michio Suzuki,Tsutomu Takahashi,Masahide Usami,Masaki Kodaira,Kyota Watanabe,Tsukasa Sasaki,Hitoshi Kuwabara,Mamoru Tochigi,Fumichika Nishimura,Hidenori Yamasue,Yosuke Eriguchi,Seico Benner,Masaki Kojima,Walid Yassin,Toshio Munesue,Shigeru Yokoyama,Ryo Kimura,Yasuko Funabiki,Hirotaka Kosaka,Makoto Ishitobi,Tetsuro Ohmori,Shusuke Numata,Takeo Yoshikawa,Tomoko Toyota,Kazuhiro Yamakawa,Toshimitsu Suzuki,Yushi Inoue,Kentaro Nakaoka,Yu-ichi Goto,Masumi Inagaki,Naoki Hashimoto,Ichiro Kusumi,Shuraku Son,Toshiya Murai,Tempei Ikegame,Naohiro Okada,Kiyoto Kasai,Shohko Kunimoto,Daisuke Mori,Nakao Iwata,Norio Ozaki +80 more
TL;DR: An etiological overlap of ASD and SCZ is suggested and multiple disease-relevant genes in eight well-known ASD/SCZ-associated CNV loci are identified, which provide biological insights into these disorders.
Journal ArticleDOI
High-resolution copy number variation analysis of schizophrenia in Japan
Itaru Kushima,Branko Aleksic,Masahiro Nakatochi,Teppei Shimamura,Tomoko Shiino,Akira Yoshimi,Hiroki Kimura,Yuto Takasaki,Chaochen Wang,Jingrui Xing,Kanako Ishizuka,Tomoko Oya-Ito,Yukako Nakamura,Yuko Arioka,T Maeda,Maeri Yamamoto,Mami Yoshida,H Noma,Shuko Hamada,Maki Morikawa,Yota Uno,Takashi Okada,Tetsuya Iidaka,Shuji Iritani,Toshimichi Yamamoto,Mitsuhiro Miyashita,Akiko Kobori,Makoto Arai,Masanari Itokawa,M C Cheng,Y A Chuang,Chia-Hsiang Chen,Michio Suzuki,Tsutomu Takahashi,Ryota Hashimoto,Hidenaga Yamamori,Yuka Yasuda,Yuichiro Watanabe,Ayako Nunokawa,Toshiyuki Someya,Masashi Ikeda,Tomoko Toyota,Takeo Yoshikawa,Shusuke Numata,Tetsuro Ohmori,Shohko Kunimoto,Daisuke Mori,Nakao Iwata,Norio Ozaki +48 more
TL;DR: The study shows the high genetic heterogeneity of SCZ and its clinical features and raises the possibility that genomic instability is involved in its pathogenesis, which may be related to the increased burden of de novo CNVs and variable expressivity of CNVs.
Journal ArticleDOI
Relationship between social support during pregnancy and postpartum depressive state: a prospective cohort study.
Mako Morikawa,Takashi Okada,Masahiko Ando,Branko Aleksic,Shohko Kunimoto,Yukako Nakamura,Chika Kubota,Yota Uno,Ai Tamaji,Norika Hayakawa,Kaori Furumura,Tomoko Shiino,Tokiko Morita,Naoko Ishikawa,Harue Ohoka,Hinako Usui,Naomi Banno,Satomi Murase,Setsuko Goto,Atsuko Kanai,Tomoko Masuda,Norio Ozaki +21 more
TL;DR: It is suggested that having a larger number of supportive persons during pregnancy helps protect against postpartum depression, and that this effect is greater in depressive than non-depressive pregnant women.
Journal ArticleDOI
Mutations in NOTCH3 cause the formation and retention of aggregates in the endoplasmic reticulum, leading to impaired cell proliferation
Keikichi Takahashi,Kayo Adachi,Kaichi Yoshizaki,Shohko Kunimoto,Raj N. Kalaria,Atsushi Watanabe +5 more
TL;DR: It is suggested that prolonged retention of mutant Notch3 aggregates in the ER decreases cell growth and increases sensitivity to other stresses, and it is also possible that the aggregate-prone property of mutant notch3 contributes to a pathogenic mechanism underlying CADASIL.
Journal ArticleDOI
Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis.
Akihiro Mouri,M. Ukai,Mizuki Uchida,Sho Hasegawa,Masayuki Taniguchi,Takahiro Ito,Hirotake Hida,Akira Yoshimi,Kiyofumi Yamada,Shohko Kunimoto,Norio Ozaki,Toshitaka Nabeshima,Yukihiro Noda +12 more
TL;DR: In conclusion, social avoidance induced by social defeat stress exposure as juveniles are more persistent than that as adults and are associated with suppression of hippocampal neurogenesis via glucocorticoid receptors.