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Christopher Toomajian
Researcher at Kansas State University
Publications - 30
Citations - 6816
Christopher Toomajian is an academic researcher from Kansas State University. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 21, co-authored 30 publications receiving 6378 citations. Previous affiliations of Christopher Toomajian include University of Chicago & Northwestern University.
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Journal ArticleDOI
The pattern of polymorphism in Arabidopsis thaliana.
Magnus Nordborg,Tina T. Hu,Yoko Ishino,Jinal Jhaveri,Christopher Toomajian,Honggang Zheng,E. G. Bakker,Peter Calabrese,Jean Gladstone,Rana Goyal,Mattias Jakobsson,Sung K. Kim,Yuri Morozov,Badri Padhukasahasram,Vincent Plagnol,Noah A. Rosenberg,Chitiksha Shah,Jeffrey D. Wall,Jue Wang,Keyan Zhao,Theodore S. Kalbfleisch,Vincent P. Schulz,Martin Kreitman,Joy Bergelson +23 more
TL;DR: The data support the utility of A. thaliana as a model for evolutionary functional genomics and suggest there is a genome-wide excess of rare alleles and too much variation between genomic regions in the level of polymorphism.
Journal ArticleDOI
An Arabidopsis Example of Association Mapping in Structured Samples
Keyan Zhao,Maria José Aranzana,Sung K. Kim,Clare Lister,Chikako Shindo,Chunlao Tang,Christopher Toomajian,Honggang Zheng,Caroline Dean,Paul Marjoram,Magnus Nordborg +10 more
TL;DR: By combining the association results with results from linkage mapping in F2 crosses, this study identifies one previously known true positive and several promising new associations, but also demonstrates the existence of both false positives and false negatives.
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Common sequence polymorphisms shaping genetic diversity in Arabidopsis thaliana.
Richard M. Clark,Gabriele Schweikert,Christopher Toomajian,Stephan Ossowski,Georg Zeller,Paul Shinn,Norman Warthmann,Tina T. Hu,Glenn Fu,David A. Hinds,Huaming Chen,Kelly A. Frazer,Daniel H. Huson,Bernhard Schölkopf,Magnus Nordborg,Gunnar Rätsch,Joseph R. Ecker,Detlef Weigel +17 more
TL;DR: To examine the patterns of, and the forces shaping, sequence variation in Arabidopsis thaliana, high-density array resequencing of 20 diverse strains was performed and nonredundant single-nucleotide polymorphisms were identified at moderate false discovery rates.
Journal ArticleDOI
Multiple reference genomes and transcriptomes for Arabidopsis thaliana
Xiangchao Gan,Oliver Stegle,Jonas Behr,Joshua G. Steffen,Philipp Drewe,Katie L. Hildebrand,Rune Lyngsoe,Sebastian J. Schultheiss,Edward J. Osborne,Vipin T. Sreedharan,André Kahles,Regina Bohnert,Géraldine Jean,Paul S. Derwent,Paul J. Kersey,Eric J. Belfield,Nicholas P. Harberd,Eric Kemen,Christopher Toomajian,Paula X. Kover,Richard M. Clark,Gunnar Rätsch,Richard Mott +22 more
TL;DR: Genetic differences between Arabidopsis thaliana accessions underlie the plant’s extensive phenotypic variation, and until now these have been interpreted largely in the context of the annotated reference accession Col-0.
Journal ArticleDOI
Adaptation to climate across the Arabidopsis thaliana genome.
Angela M. Hancock,Benjamin Brachi,Nathalie Faure,Matthew W. Horton,Lucien B. Jarymowycz,F. Gianluca Sperone,Christopher Toomajian,Fabrice Roux,Joy Bergelson +8 more
TL;DR: A genome-wide scan to identify climate-adaptive genetic loci and pathways in the plant Arabidopsis thaliana provided a set of candidates for dissecting the molecular bases of climate adaptations, as well as insights about the prevalence of selective sweeps, which has implications for predicting the rate of adaptation.