C
Claire Desnos
Researcher at Centre national de la recherche scientifique
Publications - 27
Citations - 3475
Claire Desnos is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Exocytosis & Vesicular monoamine transporter. The author has an hindex of 19, co-authored 27 publications receiving 2969 citations. Previous affiliations of Claire Desnos include Paris Descartes University.
Papers
More filters
Journal ArticleDOI
Rab27a and Rab27b control different steps of the exosome secretion pathway
Matias Ostrowski,Nuno Carmo,Sophie Krumeich,Sophie Krumeich,Isabelle Fanget,Graça Raposo,Graça Raposo,Ariel Savina,Ariel Savina,Catarina Moita,Kristine Schauer,Kristine Schauer,Alistair N. Hume,Rui P. Freitas,Bruno Goud,Bruno Goud,Philippe Benaroch,Philippe Benaroch,Nir Hacohen,Nir Hacohen,Mitsunori Fukuda,Claire Desnos,Miguel C. Seabra,Miguel C. Seabra,Miguel C. Seabra,François Darchen,Sebastian Amigorena,Sebastian Amigorena,Luis F. Moita,Clotilde Théry,Clotilde Théry +30 more
TL;DR: The results therefore strengthen the link between MVEs and exosomes, and introduce ways of manipulating exosome secretion in vivo.
Journal ArticleDOI
MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes
Aziz El-Amraoui,Jean-Sébastien Schonn,Polonca Küssel-Andermann,Stéphane Blanchard,Claire Desnos,Jean-Pierre Henry,Uwe Wolfrum,François Darchen,Christine Petit +8 more
TL;DR: It is proposed that a molecular complex composed of Rab27A, MyRIP and myosin VIIa bridges retinal melanosomes to the actin cytoskeleton and thereby mediates the local trafficking of these organelles.
Journal ArticleDOI
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites
Claire Desnos,Jean-Sébastien Schonn,Sébastien Huet,Viet Samuel Tran,Aziz El-Amraoui,Graça Raposo,Isabelle Fanget,Catherine Chapuis,Gaël Ménasché,Geneviève de Saint Basile,Christine Petit,Sophie Cribier,Jean-Pierre Henry,François Darchen +13 more
TL;DR: It is proposed that Rab27A and MyRIP link SGs to F-actin and control their motion toward release sites through the actin cortex and control the mobility of SGs in adrenal chromaffin cells and PC12 cells.
Journal ArticleDOI
Polarized secretion of lysosomes at the B cell synapse couples antigen extraction to processing and presentation.
Maria-Isabel Yuseff,Anne Reversat,Danielle Lankar,Jheimmy Diaz,Isabelle Fanget,Paolo Pierobon,Violaine Randrian,Nathanael Larochette,Fulvia Vascotto,Chantal Desdouets,Bertrand Jauffred,Yohanns Bellaïche,Stéphane Gasman,François Darchen,Claire Desnos,Ana-Maria Lennon-Duménil +15 more
TL;DR: Regulation of B lymphocyte polarity emerges as a central mechanism that couples Ag extraction to Ag processing and presentation.
Journal ArticleDOI
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia
Pedro Monteiro,Pedro Monteiro,Carine Rossé,Carine Rossé,Antonio Castro-Castro,Antonio Castro-Castro,Marie Irondelle,Marie Irondelle,Emilie Lagoutte,Emilie Lagoutte,Perrine Paul-Gilloteaux,Perrine Paul-Gilloteaux,Claire Desnos,Claire Desnos,Etienne Formstecher,François Darchen,François Darchen,David Perrais,David Perrais,Alexis Gautreau,Maud Hertzog,Maud Hertzog,Philippe Chavrier,Philippe Chavrier +23 more
TL;DR: WASH and exocyst promote pericellular matrix degradation and tumor cell invasion by enabling localized exocytosis of MT1-MMP from late endosomes.