Kristine Schauer

TL;DR: The results therefore strengthen the link between MVEs and exosomes, and introduce ways of manipulating exosome secretion in vivo.

TL;DR: It is becoming clear that the chemical nature of the substrates, the energetic requirements for transport and the subsequent translocation across the cytoplasmic membrane can differ from those of the well-studied systems for iron complexes and vitamin B12.

TL;DR: It is shown that active focal adhesion kinase (FAK), an established marker of integrin–ECM downstream signalling, localizes with active integrins on endosomes and becomes activated on them, suggesting a role for endocytosis in enhancing distinct integrin downstream signalling events.

TL;DR: It is demonstrated that ExbB/ExbD/TonB and FrpB4 deficient bacteria are unable to efficiently scavenge nickel at low pH, which mimics those encountered by H. pylori during stomach colonization, under which nickel supply and full urease activity are essential to combat acidity.

TL;DR: BIN1/M-Amphiphysin2, a protein involved in T-tubule biogenesis in muscle cells and frequently mutated in centronuclear myopathies, clusters PtdIns(4,5)P2 to recruit its downstream partner dynamin and it is proposed that this mechanism plays a key role in the recruitment of downstream phosphoinositide-binding proteins.