Cristiano A. Köhler

TL;DR: This large‐scale meta‐analysis confirms that SMI patients have significantly increased risk of CVD and CVD‐related mortality, and that elevated body mass index, antipsychotic use, andCVD screening and management require urgent clinical attention.

TL;DR: A systematic review and meta‐analysis of studies that measured cytokine and chemokine levels in individuals with major depressive disorder (MDD) compared to healthy controls (HCs) is conducted.

TL;DR: An updated meta-analysis of studies that measured peripheral levels of cytokines and chemokines during antidepressant treatment in patients with MDD indicates that antidepressants decrease several markers of peripheral inflammation, but does not provide evidence that reductions in peripheral inflammation are associated with antidepressant treatment response.

TL;DR: It is suggested that AD is accompanied by a peripheral inflammatory response and that IL-6 may be a useful biological marker to correlate with the severity of cognitive impairment and inversely correlated with mean MMSE scores.

TL;DR: The data suggest that peripheral BDNF levels, more clearly in plasma than in serum, is a potential biomarker of disease activity in BD, but not a biomarkers of stage.