C
Curtis Cai
Publications - 8
Citations - 364
Curtis Cai is an academic researcher. The author has contributed to research in topics: Biology & Immune system. The author has an hindex of 4, co-authored 8 publications receiving 364 citations.
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Journal ArticleDOI
Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant
Yutai Gao,Curtis Cai,Alba Grifoni,Thomas R. Müller,Julia Niessl,Anna Olofsson,Marion Humbert,Lotta Hansson,Anders Österborg,Peter Bergman,Puran Chen,Annika Olsson,Johan Sundberg,Daniela Weiskopf,David Price,Hans-Gustaf Ljunggren,Annika C. Karlsson,Alessandro Sette,Soo Aleman,Marcus Buggert +19 more
TL;DR: In this article , the authors report that SARS-CoV-2 spike-specific CD4+ and CD8+ T cells induced by prior infection or BNT162b2 vaccination provide extensive immune coverage against B.1.529.
Journal ArticleDOI
Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination
Yutai Gao,Curtis Cai,David J. Wullimann,Julia Niessl,Olga Rivera-Ballesteros,Puran Chen,J Lange,Angelica Cuapio,Ola Blennow,Lotta Hansson,Stephan Mielke,Piotr Nowak,Jan Vesterbacka,Mira Akber,André Perez-Potti,Takuya Sekine,Thomas R. Müller,Caroline Boulouis,Tobias Kammann,Tiphaine Parrot,Jagadeeswara Rao Muvva,Michał J. Sobkowiak,Katie Healy,Gordana Bogdanovic,Sandra Muschiol,Gunnar Söderdahl,Anders Österborg,Fredrika Hellgren,Alba Grifoni,Daniela Weiskopf,Alessandro Sette,Karin Loré,Margaret Sällberg Chen,Per Ljungman,Johan Sundberg,C. I. Edvard Smith,Peter Bergman,Hans-Gustaf Ljunggren,Soo Aleman,Marcus Buggert +39 more
TL;DR: In this article , the authors assessed the single-cell profile of SARS-CoV-2-specific T cells post-mRNA vaccination in healthy individuals and patients with various forms of immunodeficiencies.
Posted ContentDOI
Ancestral SARS-CoV-2-specific T cells cross-recognize Omicron (B.1.1.529)
Yutai Gao,Curtis Cai,Alba Grifoni,Thomas Müller,Julia Niessl,Anna Olofsson,Marion Humbert,Lotta Hansson,Anders Österborg,Peter Bergman,Puran Chen,Annika Olsson,Johan Sundberg,Daniela Weiskopf,David Price,Hans-Gustaf Ljunggren,Annika C. Karlsson,Alessandro Sette,Soo Aleman,Marcus Buggert +19 more
TL;DR: It is reported here that SARS-CoV-2 spike-specific CD4+ and CD8+ T cells induced by prior infection and, more extensively, by mRNA vaccination provide comprehensive heterologous immune reactivity against B.1.1 .1.529.
Journal ArticleDOI
Ancestral SARS-CoV-2-specific T cells cross-recognize Omicron
Yutai Gao,Curtis Cai,Alba Grifoni,Thomas R. Müller,Julia Niessl,Anna Olofsson,Marion Humbert,Lotta Hansson,Anders Österborg,Peter Bergman,Puran Chen,Annika Olsson,Johan Sundberg,Daniela Weiskopf,David Price,Hans-Gustaf Ljunggren,Annika C. Karlsson,Alessandro Sette,Soo Aleman,Marcus Buggert +19 more
TL;DR: In this paper , SARS-CoV-2 spike-specific CD4+ and CD8+ T cells induced by prior infection or BNT162b2 vaccination provide extensive immune coverage against B.1.1 .
Journal ArticleDOI
Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age
Marion Humbert,Anna Olofsson,David J. Wullimann,Julia Niessl,Emma B. Hodcroft,Curtis Cai,Yutai Gao,Ebba Sohlberg,Robert Dyrdak,Flora Mikaeloff,Ujjwal Neogi,J. Albert,Karl-Johan Malmberg,Fridtjof Lund-Johansen,Soo Aleman,Linda Björkhem-Bergman,Maria C. Jenmalm,Hans-Gustaf Ljunggren,Marcus Buggert,Annika C. Karlsson +19 more
TL;DR: In this paper , the authors provided evidence that functional pre-existing SARS-CoV-2reactive memory CD4+ T cells are elicited in early childhood and linked to seroconversion with the seasonal coronavirus OC43 but not many other viral infections.