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André Perez-Potti
Researcher at Karolinska University Hospital
Publications - 14
Citations - 2290
André Perez-Potti is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: T cell & Cytotoxic T cell. The author has an hindex of 8, co-authored 12 publications receiving 1383 citations. Previous affiliations of André Perez-Potti include Karolinska Institutet & University College Dublin.
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Journal ArticleDOI
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Takuya Sekine,André Perez-Potti,Olga Rivera-Ballesteros,Kristoffer Strålin,Jean Baptiste Gorin,Annika Olsson,Sian Llewellyn-Lacey,Habiba Kamal,Gordana Bogdanovic,Sandra Muschiol,David J. Wullimann,Tobias Kammann,Johanna Emgård,Tiphaine Parrot,Elin Folkesson,Olav Rooyackers,Lars Eriksson,Jan-Inge Henter,Anders Sönnerborg,Tobias Allander,Jan Albert,Morten Nielsen,Jonas Klingström,Sara Gredmark-Russ,Niklas K. Björkström,Johan K. Sandberg,David Price,Hans-Gustaf Ljunggren,Soo Aleman,Marcus Buggert +29 more
TL;DR: It is shown that SARS-CoV-2 elicits robust, broad and highly functional memory T cell responses, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19.
Posted ContentDOI
Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19
Takuya Sekine,André Perez-Potti,Olga Rivera-Ballesteros,Kristoffer Strålin,Jean-Baptiste Gorin,Annika Olsson,Sian Llewellyn-Lacey,Habiba Kamal,Gordana Bogdanovic,Sandra Muschiol,David J. Wullimann,Tobias Kammann,Johanna Emgård,Tiphaine Parrot,Elin Folkesson,Olav Rooyackers,Olav Rooyackers,Lars Eriksson,Lars Eriksson,Anders Sönnerborg,Tobias Allander,Tobias Allander,Jan Albert,Jan Albert,Morten Nielsen,Jonas Klingström,Sara Gredmark-Russ,Niklas K. Björkström,Johan K. Sandberg,David Price,Hans-Gustaf Ljunggren,Soo Aleman,Marcus Buggert +32 more
TL;DR: The collective dataset shows that SARS-CoV-2 elicits robust memory T cell responses akin to those observed in the context of successful vaccines, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19 also in seronegative individuals.
Journal ArticleDOI
MAIT cell activation and dynamics associated with COVID-19 disease severity.
Tiphaine Parrot,Jean-Baptiste Gorin,Andrea Ponzetta,Kimia T. Maleki,Tobias Kammann,Johanna Emgård,André Perez-Potti,Takuya Sekine,Olga Rivera-Ballesteros,Sara Gredmark-Russ,Olav Rooyackers,Olav Rooyackers,Elin Folkesson,Elin Folkesson,Lars Eriksson,Lars Eriksson,Anna Norrby-Teglund,Hans-Gustaf Ljunggren,Niklas K. Björkström,Soo Aleman,Soo Aleman,Marcus Buggert,Jonas Klingström,Kristoffer Strålin,Kristoffer Strålin,Johan K. Sandberg +25 more
TL;DR: Findings indicate that MAIT cells are engaged in the immune response against SARS-CoV-2 and suggest their possible involvement in COVID-19 immunopathogenesis.
Journal ArticleDOI
Influence of Size and Shape on the Anatomical Distribution of Endotoxin-Free Gold Nanoparticles
Laura Talamini,Martina Bruna Violatto,Qi Cai,Marco P. Monopoli,Marco P. Monopoli,Karsten Kantner,Željka Krpetić,Željka Krpetić,André Perez-Potti,Jennifer Cookman,David Garry,Camila P. Silveira,Luca Boselli,Beatriz Pelaz,Tommaso Serchi,Sébastien Cambier,Arno C. Gutleb,Neus Feliu,Neus Feliu,Yan Yan,Mario Salmona,Wolfgang J. Parak,Kenneth A. Dawson,Paolo Bigini +23 more
TL;DR: The study reveals that the size and the shape greatly influence the kinetics of accumulation and excretion of GNPs in filter organs, and can be considered as a reliable starting point to drive the synthesis and the functionalization of potential candidates for theranostic purposes in many fields of research.
Journal ArticleDOI
TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells
Takuya Sekine,André Perez-Potti,Son Nguyen,Jean-Baptiste Gorin,Vincent H. Wu,Emma Gostick,Sian Llewellyn-Lacey,Quirin Hammer,Sara Falck-Jones,Sindhu Vangeti,Meng Yu,Anna Smed-Sörensen,Ahmed Gaballa,Michael Uhlin,Michael Uhlin,Johan K. Sandberg,Christian Brander,Christian Brander,Piotr Nowak,Paul A. Goepfert,David Price,Michael R. Betts,Marcus Buggert +22 more
TL;DR: It is demonstrated that circulating TOX+ CD8+ T cells exist in most humans, but that TOX is not exclusively associated with exhaustion.