D
Daniel Keller
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 40
Citations - 2641
Daniel Keller is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Computer science & Biology. The author has an hindex of 14, co-authored 33 publications receiving 1801 citations. Previous affiliations of Daniel Keller include University of California, San Diego & Salk Institute for Biological Studies.
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Journal ArticleDOI
Reconstruction and Simulation of Neocortical Microcircuitry
Henry Markram,Henry Markram,Eilif Muller,Srikanth Ramaswamy,Michael W. Reimann,Marwan Abdellah,Carlos Aguado Sanchez,Anastasia Ailamaki,Lidia Alonso-Nanclares,Lidia Alonso-Nanclares,Nicolas Antille,Selim Arsever,Guy Antoine Atenekeng Kahou,Thomas K. Berger,Ahmet Bilgili,Nenad Buncic,Athanassia Chalimourda,Giuseppe Chindemi,Jean Denis Courcol,Fabien Delalondre,Vincent Delattre,Shaul Druckmann,Shaul Druckmann,Raphael Dumusc,James Dynes,Stefan Eilemann,Eyal Gal,Michael Gevaert,Jean Pierre Ghobril,Albert Gidon,Joe W. Graham,Anirudh Gupta,Valentin Haenel,Etay Hay,Thomas Heinis,Thomas Heinis,Juan Hernando,Michael L. Hines,Lida Kanari,Daniel Keller,John Kenyon,Georges Khazen,Yihwa Kim,James G. King,Zoltán F. Kisvárday,Pramod Kumbhar,Sebastien Lasserre,Jean Vincent Le Bé,Bruno R. C. Magalhães,Angel Merchán-Pérez,Angel Merchán-Pérez,Julie Meystre,Benjamin Roy Morrice,Jeffrey Muller,Alberto Muñoz-Céspedes,Alberto Muñoz-Céspedes,Shruti Muralidhar,Keerthan Muthurasa,Daniel Nachbaur,Taylor Howard Newton,Max Nolte,Aleksandr Ovcharenko,Juan Palacios,Luis Pastor,Rodrigo Perin,Rajnish Ranjan,Rajnish Ranjan,Imad Riachi,José-Rodrigo Rodríguez,José-Rodrigo Rodríguez,Juan Luis Riquelme,Christian Rössert,Konstantinos Sfyrakis,Ying Shi,Ying Shi,Julian C. Shillcock,Gilad Silberberg,Ricardo Silva,Farhan Tauheed,Martin Telefont,Maria Toledo-Rodriguez,Thomas Tränkler,Werner Van Geit,Jafet Villafranca Diaz,Richard Walker,Yun Wang,Yun Wang,Stefano M. Zaninetta,Javier DeFelipe,Javier DeFelipe,Sean Hill,Idan Segev,Felix Schürmann +92 more
TL;DR: A first-draft digital reconstruction of the microcircuitry of somatosensory cortex of juvenile rat is presented, finding a spectrum of network states with a sharp transition from synchronous to asynchronous activity, modulated by physiological mechanisms.
Journal ArticleDOI
Cell Densities in the Mouse Brain: A Systematic Review.
TL;DR: An exhaustive review of the literature is performed to establish the current state of knowledge on cell numbers in mouse brain regions, arguably the most fundamental property to measure when attempting to understand a brain.
Journal ArticleDOI
A Cell Atlas for the Mouse Brain.
TL;DR: A first 3D cell atlas for the whole mouse brain is provided, showing cell positions constructed algorithmically from whole brain Nissl and gene expression stains, and compared against values from the literature.
Journal ArticleDOI
The neocortical microcircuit collaboration portal: a resource for rat somatosensory cortex
Srikanth Ramaswamy,Jean-Denis Courcol,Marwan Abdellah,Stanislaw Adaszewski,Nicolas Antille,Selim Arsever,Guy Atenekeng,Ahmet Bilgili,Yury Brukau,Athanassia Chalimourda,Giuseppe Chindemi,Fabien Delalondre,Raphael Dumusc,Stefan Eilemann,Michael Gevaert,Padraig Gleeson,Joe W. Graham,Juan Hernando,Lida Kanari,Yury Katkov,Daniel Keller,James G. King,Rajnish Ranjan,Michael W. Reimann,Christian Rössert,Ying Shi,Julian C. Shillcock,Martin Telefont,Werner Van Geit,Jafet Villafranca Diaz,Richard Walker,Yun Wang,Yun Wang,Stefano M. Zaninetta,Javier DeFelipe,Javier DeFelipe,Sean Hill,Jeffrey Muller,Idan Segev,Felix Schürmann,Eilif Muller,Henry Markram +41 more
TL;DR: A multi-constraint, data-driven process to digitally reconstruct, and simulate prototypical neocortical microcircuitry, using sparse experimental data is established and considered a major step in the development of in silica neuroscience.
Journal ArticleDOI
Calmodulin Activation by Calcium Transients in the Postsynaptic Density of Dendritic Spines
Daniel Keller,Kevin M. Franks,Kevin M. Franks,Thomas M. Bartol,Thomas M. Bartol,Terrence J. Sejnowski,Terrence J. Sejnowski +6 more
TL;DR: A Monte Carlo model of intracellular calcium dynamics within the spine that included calcium binding proteins, calcium transporters and ion channels activated by voltage and glutamate binding is developed and could be used in other signaling pathways.