Daniela Penzkofer

TL;DR: Regional LNA-92a delivery reduces miR- 92a levels and infarct size and postischemic loss of function and might be a novel therapeutic tool to preserve cardiac function after ischemia.

TL;DR: It is indicated that inhibition of endothelial miR-92a attenuates neointimal lesion formation by accelerating re-endothelialization and thus represents a putative novel mechanism to enhance the functional recovery following vascular injury.

TL;DR: Overall, the absence of TLR-3 is associated with lower cumulative kidney damage and maintained renal blood perfusion within the first 24 hours of reperfusion and it is concluded that TLr-3 seems to participate in the pathogenesis of early acute kidney injury.

TL;DR: It is demonstrated that deletion of miR-92a is sufficient to induce a developmental skeletal defect in mice and not reduce circulating or bone marrow-derived hematopoietic cells, but induces skeletal defects.

TL;DR: It is shown that Bβ15–42 alleviates early functional and morphological kidney damage as soon as 1 h and 3 h after ischemia and reperfusion, and may act as a potent renoprotective agent by preserving the endothelial and vascular integrity.