Danielle E. Bear

TL;DR: A pragmatic, randomized trial involving adults with an unplanned admission to one of 33 English intensive care units found no significant difference in 30-day mortality associated with the route of delivery of early nutritional support in critically ill adults.

TL;DR: Network analysis revealed a close and direct relationship between bioenergetic impairment and reduction in muscle mass and between intramuscular inflammation and impaired anabolic signaling.

TL;DR: Clinicians should integrate nutritional assessment with muscle mass measurements for optimal evaluation of these two interrelated entities to tailor interventions appropriately and design of monitoring/evaluation and discharge plans need to include multimodal interventions with nutrition and physical exercise that are key to preserve patient's muscle mass and function in clinical and community settings.

TL;DR: Recommendations to assist the clinician in the optimal management of patients at risk of low muscle mass include place muscle mass at the core of nutritional assessment and management strategies and optimize nutrition to focus on muscle mass gain versus weight gain alone.

TL;DR: Current evidence on GI dysfunction is scarce, partially due to the lack of precise definitions, and the use of core sets of monitoring and outcomes are required to improve the consistency of future studies.