D
David A. Baker
Researcher at University of London
Publications - 118
Citations - 6758
David A. Baker is an academic researcher from University of London. The author has contributed to research in topics: Plasmodium falciparum & Gene. The author has an hindex of 42, co-authored 102 publications receiving 5935 citations. Previous affiliations of David A. Baker include Arizona State University & University of Hull.
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Journal ArticleDOI
Fos protein expression and cocaine-seeking behavior in rats after exposure to a cocaine self-administration environment
Janet L. Neisewander,David A. Baker,Rita A. Fuchs,Ly T.L. Tran-Nguyen,Art J. Palmer,John F. Marshall +5 more
TL;DR: The results suggest that different neural circuits may be involved in the incentive motivational effects of cocaine-paired environmental stimuli versus priming injections and that the anterior cingulate may be part of a common pathway for both.
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A transcriptional switch underlies commitment to sexual development in malaria parasites.
Björn F.C. Kafsack,Núria Rovira-Graells,Taane G. Clark,Cristina Bancells,Valerie M. Crowley,Susana Campino,April E. Williams,Laura Drought,Dominic P. Kwiatkowski,David A. Baker,Alfred Cortés,Manuel Llinás +11 more
TL;DR: Findings identify PfAP2-G as a master regulator of sexual-stage development in malaria parasites and mark the first discovery of a transcriptional switch controlling a differentiation decision in protozoan parasites.
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The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification.
Jason A. Young,Quinton L. Fivelman,Peter L. Blair,Patricia de la Vega,Karine G. Le Roch,Yingyao Zhou,Daniel J. Carucci,David A. Baker,Elizabeth A. Winzeler +8 more
TL;DR: Light is shed on the components of molecular mechanisms underlying parasite sexual development and other areas of malarial parasite biology by applying a novel knowledge-based data-mining algorithm termed ontology-based pattern identification (OPI).
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A Plant-Like Kinase in Plasmodium falciparum Regulates Parasite Egress from Erythrocytes
Jeffrey D. Dvorin,Jeffrey D. Dvorin,Derek C. Martyn,Saurabh D. Patel,Saurabh D. Patel,Joshua S. Grimley,Christine R. Collins,Christine S. Hopp,A. Taylor Bright,Scott J. Westenberger,Elizabeth A. Winzeler,Elizabeth A. Winzeler,Michael J. Blackman,David A. Baker,Thomas J. Wandless,Manoj T. Duraisingh +15 more
TL;DR: It is found that the plant-like calcium-dependent protein kinase PfCDPK5, which is expressed in invasive merozoite forms of Plasmodium falciparum, was critical for egress from the human host erythrocyte, an essential step in the parasite life cycle.
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Group II Metabotropic Glutamate Receptors Modulate Extracellular Glutamate in the Nucleus Accumbens
TL;DR: Three conclusions are supported: 1) group II mGluRs regulate both vesicular and nonvesicular release of glutamate in the nucleus accumbens, 2) there is tonic in vivo stimulation of mGLUR2/3 by endogenous glutamate, and 3) modulation of group II gluRs of extracellular glutamate is Ca(2+)- and PKA-dependent.