D
David Eisenberg
Researcher at Technion – Israel Institute of Technology
Publications - 719
Citations - 120468
David Eisenberg is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Amyloid & Protein structure. The author has an hindex of 156, co-authored 697 publications receiving 112460 citations. Previous affiliations of David Eisenberg include Howard Hughes Medical Institute & Hebrew University of Jerusalem.
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Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
Celia W. Goulding,Marcin I. Apostol,Michael R. Sawaya,Martin L. Phillips,Angineh Parseghian,David Eisenberg +5 more
TL;DR: It is hypothesized that Mtb FolB displays cooperativity in substrate binding to regulate the cellular concentration of 7,8-dihydroneopterin, so that it may function not only as a precursor to folate but also as an antioxidant for the survival of M.tuberculosis against host defenses.
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Implications for Alzheimer’s disease of an atomic resolution structure of amyloid-β(1–42) fibrils
TL;DR: Two independent studies simultaneously describe identical, disease-relevant fibrils that form the plaques in diseased brains, and confidence in the amyloid-β(1–42) structure is reinforced by the essentially identical results of the two independent studies.
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Cooperative Catalysis for Selective Alcohol Oxidation with Molecular Oxygen.
TL;DR: It is proposed that the reaction should not be viewed as occurring at an active site, but rather at an 'active doughnut'-the volume surrounding the base of a carbon-supported metal-oxide particle.
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Utilizing logical relationships in genomic data to decipher cellular processes
TL;DR: The method has been applied fruitfully to both phylogenetic and microarray expression data, and has been used to associate logical combinations of protein activity with disease state phenotypes, revealing previously unknown ternary relationships among proteins, and illustrating the inherent complexities that arise in biological data.
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A rational synthesis of hierarchically porous, N-doped carbon from Mg-based MOFs: understanding the link between nitrogen content and oxygen reduction electrocatalysis.
David Eisenberg,Wowa Stroek,Norbert J. Geels,Stefania Tanase,Marilena Ferbinteanu,Simon J. Teat,Pierre Mettraux,Ning Yan,Gadi Rothenberg +8 more
TL;DR: A linear relation was found between synthesis pH and K/H ratio in the resultant mixture, establishing the tunability of the synthesis and isolate the positive correlation between nitrogen content and electrocatalytic oxygen reduction ORR activity in this class of metal-free, N-doped, porous carbons.