Anja C. Roden

TL;DR: The SP142 assay was an outlier that detected significantly less PD-L1 expression in tumor cells and immune cells, and Evaluation of intraclass correlation coefficients (ICCs) between antibodies to quantify interassay variability showed high concordance between antibodies for tumor cell scoring and lower levels of Concordance for immune cell scoring.

TL;DR: IHC scoring correlates with FISH and may be a useful algorithm in testing ALK+ by FISH in non-small cell lung carcinoma, similar to human epidermal growth factor-2 testing in breast cancer.

TL;DR: It is shown that levels of T cells in peripheral lymphoid tissues of mice are increased by androgen deprivation, and T cells from these mice transiently proliferate more vigorously to TCR- and CD28-mediated costimulation as well as to Ag-specific activation.

TL;DR: The questions cover topics such as the best IHC markers for distinguishing NSCLC subtypes, differences in thyroid transcription factor 1 clones, and the utility of IHC in diagnosing uncommon subtypes of lung cancer and distinguishing primary from metastatic tumors.

TL;DR: B7-H1 is expressed in a substantial proportion of malignant pleural mesotheliomas and is associated with poor survival and may have important therapeutic implications for the management of mal cancers.