D
Dhileep Sivam
Researcher at Washington University in St. Louis
Publications - 13
Citations - 3237
Dhileep Sivam is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Gene & Temporal resolution. The author has an hindex of 9, co-authored 13 publications receiving 2892 citations. Previous affiliations of Dhileep Sivam include Seattle Biomed & University of Washington.
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Journal ArticleDOI
The genome of the kinetoplastid parasite, Leishmania major.
Alasdair Ivens,Christopher S. Peacock,Elizabeth A. Worthey,Lee Murphy,Gautam Aggarwal,Matthew Berriman,Ellen Sisk,Marie-Adèle Rajandream,Ellen Adlem,Rita Aert,Atashi Anupama,Zina Apostolou,Philip Attipoe,Nathalie Bason,Christopher Bauser,Alfred Beck,Stephen M. Beverley,Gabriella Bianchettin,K. Borzym,G. Bothe,Carlo V. Bruschi,Carlo V. Bruschi,Matt Collins,Eithon Cadag,Laura Ciarloni,Christine Clayton,Richard M.R. Coulson,Ann Cronin,Angela K. Cruz,Robert L. Davies,Javier G. De Gaudenzi,Deborah E. Dobson,Andreas Duesterhoeft,Gholam Fazelina,Nigel Fosker,Alberto C.C. Frasch,Audrey Fraser,Monika Fuchs,Claudia Gabel,Arlette Goble,André Goffeau,David Harris,Christiane Hertz-Fowler,Helmut Hilbert,David Horn,Yiting Huang,Sven Klages,Andrew J Knights,Michael Kube,Natasha Larke,Lyudmila Litvin,Angela Lord,Tin Louie,Marco A. Marra,David Masuy,Keith R. Matthews,Shulamit Michaeli,Jeremy C. Mottram,Silke Müller-Auer,Heather Munden,Siri Nelson,Halina Norbertczak,Karen Oliver,Susan O'Neil,Martin Pentony,Thomas M. Pohl,Claire Price,Bénédicte Purnelle,Michael A. Quail,Ester Rabbinowitsch,Richard Reinhardt,Michael A. Rieger,Joel Rinta,Johan Robben,Laura Robertson,Jeronimo C. Ruiz,Simon Rutter,David L. Saunders,Melanie Schäfer,Jacquie Schein,David C. Schwartz,Kathy Seeger,Amber Seyler,Sarah Sharp,Heesun Shin,Dhileep Sivam,Rob Squares,Steve Squares,Valentina Tosato,Christy Vogt,Guido Volckaert,Rolf Wambutt,T. Warren,Holger Wedler,John Woodward,Shiguo Zhou,Wolfgang Zimmermann,Deborah F. Smith,Jenefer M. Blackwell,Kenneth Stuart,Kenneth Stuart,Bart Barrell,Peter J. Myler,Peter J. Myler +103 more
TL;DR: The organization of protein-coding genes into long, strand-specific, polycistronic clusters and lack of general transcription factors in the L. major, Trypanosoma brucei, and Tritryp genomes suggest that the mechanisms regulating RNA polymerase II–directed transcription are distinct from those operating in other eukaryotes, although the trypanosomatids appear capable of chromatin remodeling.
Journal ArticleDOI
TriTrypDB: a functional genomic resource for the Trypanosomatidae
Martin Aslett,Cristina Aurrecoechea,Matthew Berriman,John Brestelli,Brian P. Brunk,Mark Carrington,Daniel P. Depledge,Steve Fischer,Bindu Gajria,Xin Gao,Malcolm J. Gardner,Alan R. Gingle,Gregory R. Grant,Omar S. Harb,Mark Heiges,Christiane Hertz-Fowler,Robin Houston,Frank Innamorato,John Iodice,Jessica C. Kissinger,Eileen Kraemer,Wei Li,Flora J. Logan,John A. Miller,Siddhartha Mitra,Peter J. Myler,Vishal Nayak,Cary Pennington,Isabelle Phan,Deborah F. Pinney,Gowthaman Ramasamy,Matthew B. Rogers,David S. Roos,Christopher A. Ross,Dhileep Sivam,Deborah F. Smith,Ganesh Srinivasamoorthy,Christian J. Stoeckert,Sandhya Subramanian,Ryan Thibodeau,Adrian Tivey,Charles Treatman,Giles S. Velarde,Haiming Wang +43 more
TL;DR: TriTrypDB is an integrated database providing access to genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex queries driven by research and development needs, utilizing a sophisticated search strategy system.
Journal ArticleDOI
An amniote life-history database to perform comparative analyses with birds, mammals, and reptiles
Nathan Myhrvold,Elita Baldridge,Benjamin Chan,Dhileep Sivam,Daniel L. Freeman,S. K. Morgan Ernest,S. K. Morgan Ernest +6 more
TL;DR: In this article, a normalized and consolidated database of up to 29 life-history parameters, containing at least one life history parameter for 21 species of birds, mammals, and reptiles, was created.
Journal ArticleDOI
Identification of Genes Overexpressed in Head and Neck Squamous Cell Carcinoma Using a Combination of Complementary DNA Subtraction and Microarray Analysis
Douglas B. Villaret,Tongtong Wang,Davin C. Dillon,Jiangchun Xu,Dhileep Sivam,Martin A. Cheever,Steven G. Reed +6 more
TL;DR: The aim is to discover unique genes specific for squamous cell carcinoma of the head and neck for eventual development as tumor markers and vaccine candidates.
Journal ArticleDOI
Widespread variation in transcript abundance within and across developmental stages of Trypanosoma brucei
Bryan C. Jensen,Dhileep Sivam,Dhileep Sivam,Charles T. Kifer,Peter J. Myler,Peter J. Myler,Marilyn Parsons,Marilyn Parsons +7 more
TL;DR: A comprehensive analysis of mRNA expression in several stages of parasite development reveals extensive regulation of mRNA abundance associated with different life cycle and growth stages and analysis of variant surface glycoprotein gene expression reveals a more complex picture than previously thought.