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Deborah Donnell
Researcher at Fred Hutchinson Cancer Research Center
Publications - 231
Citations - 13344
Deborah Donnell is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Pre-exposure prophylaxis & Population. The author has an hindex of 49, co-authored 199 publications receiving 11097 citations. Previous affiliations of Deborah Donnell include University of California, Los Angeles & University of Washington.
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Journal ArticleDOI
Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.
Jared M. Baeten,Deborah Donnell,Deborah Donnell,Patrick Ndase,Nelly Mugo,Nelly Mugo,James D. Campbell,Jonathan Wangisi,Jordan W. Tappero,Elizabeth A. Bukusi,Craig R. Cohen,Elly Katabira,Allan R. Ronald,Allan R. Ronald,Elioda Tumwesigye,Edwin Were,Kenneth H. Fife,James Kiarie,James Kiarie,Carey Farquhar,Grace John-Stewart,Aloysious Kakia,Josephine Odoyo,Akasiima Mucunguzi,Edith Nakku-Joloba,Rogers Twesigye,Kenneth Ngure,Cosmas Apaka,Harrison Tamooh,Fridah Gabona,Andrew Mujugira,Dana Panteleeff,Katherine K. Thomas,Lara Kidoguchi,Meighan Krows,Jennifer Revall,Susan Morrison,Harald S. Haugen,Mira Emmanuel-Ogier,Lisa Ondrejcek,Robert W. Coombs,Lisa M. Frenkel,Lisa M. Frenkel,Craig W. Hendrix,Namandjé N. Bumpus,David R. Bangsberg,Jessica E. Haberer,Wendy S. Stevens,Jairam R. Lingappa,Connie Celum +49 more
TL;DR: Oral TDF and TDF-FTC both protect against HIV-1 infection in heterosexual men and women, and both study medications significantly reduced the HIV- 1 incidence among both men andWomen.
Journal ArticleDOI
Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis.
Deborah Donnell,Deborah Donnell,Jared M. Baeten,James Kiarie,James Kiarie,Katherine K. Thomas,Wendy S. Stevens,Craig R. Cohen,James McIntyre,Jairam R. Lingappa,Connie Celum +10 more
TL;DR: In this article, the effect of ART use by patients infected with HIV-1 on risk of transmission to their uninfected partners was evaluated in a randomised placebo-controlled trial that enrolled heterosexual African adults who were seropositive for both HIV and herpes simplex virus type 2.
Journal ArticleDOI
Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study
Renee Heffron,Deborah Donnell,Helen Rees,Connie Celum,Nelly Mugo,Nelly Mugo,Nelly Mugo,Edwin Were,Guy de Bruyn,Edith Nakku-Joloba,Edith Nakku-Joloba,Kenneth Ngure,James Kiarie,James Kiarie,James Kiarie,Robert W. Coombs,Jared M. Baeten +16 more
TL;DR: In this article, the authors used Cox proportional hazards regression and marginal structural modeling to assess the effect of contraceptive use on HIV-1 risk and found that women who used hormonal contraception had higher risk of acquiring HIV than those who did not.
Journal ArticleDOI
Bacterial vaginosis associated with increased risk of female-to-male HIV-1 transmission: a prospective cohort analysis among African couples.
Craig R. Cohen,Jairam R. Lingappa,Jared M. Baeten,Musa Otieno Ngayo,Carol A. Spiegel,Ting Hong,Deborah Donnell,Connie Celum,Saidi Kapiga,Sinead Delany,Elizabeth A. Bukusi +10 more
TL;DR: In a prospective study, Craig Cohen and colleagues investigate the association between bacterial vaginosis and the risk of female-to-male HIV-1 transmission.
Journal ArticleDOI
Genital HIV-1 RNA Predicts Risk of Heterosexual HIV-1 Transmission
Jared M. Baeten,Erin M. Kahle,Jairam R. Lingappa,Robert W. Coombs,Sinead Delany-Moretlwe,Edith Nakku-Joloba,Nelly Mugo,Nelly Mugo,Anna Wald,Lawrence Corey,Deborah Donnell,Deborah Donnell,Mary S. Campbell,James I. Mullins,Connie Celum +14 more
TL;DR: It is demonstrated that higher concentrations of HIV-1 RNA in genital secretions are associated with a greater risk of heterosexual transmission of HIV, and that these concentrations provide a new biomarker for predicting the infectiousness of HIV–infected individuals.