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Delphine Lissa
Researcher at Institut Gustave Roussy
Publications - 17
Citations - 806
Delphine Lissa is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Medicine & Cancer cell. The author has an hindex of 10, co-authored 12 publications receiving 672 citations. Previous affiliations of Delphine Lissa include University of Paris-Sud & French Institute of Health and Medical Research.
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Journal ArticleDOI
Autophagic removal of micronuclei.
Santiago Rello-Varona,Delphine Lissa,Shensi Shen,Mireia Niso-Santano,Laura Senovilla,Guillermo Mariño,Ilio Vitale,Mohamed Jemaà,Francis Harper,Gérard Pierron,Maria Castedo,Guido Kroemer +11 more
TL;DR: Results indicate that micron nuclei can be subjected to autophagic degradation and it can be speculated that removal of micronuclei may contribute to the genome-stabilizing effects of autophagy.
Journal ArticleDOI
Cisplatin resistance associated with PARP hyperactivation.
Judith Michels,Ilio Vitale,Lorenzo Galluzzi,Julien Adam,Ken A. Olaussen,Oliver Kepp,Laura Senovilla,Ibtissam Talhaoui,Justine Guegan,David Enot,Monique Talbot,Angélique Robin,Philippe Girard,Cedric Orear,Delphine Lissa,Abdul Qader Sukkurwala,Pauline Garcia,Parviz Behnam-Motlagh,Kimitoshi Kohno,Gen Sheng Wu,Catherine Brenner,Philippe Dessen,Murat Saparbaev,Jean-Charles Soria,Maria Castedo,Guido Kroemer +25 more
TL;DR: It is shown that PARP1 is highly expressed and constitutively hyperactivated in a majority of human CDDP-resistant cancer cells of distinct histologic origin, becoming susceptible to PARP inhibitor-induced apoptosis.
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Pro-autophagic polyphenols reduce the acetylation of cytoplasmic proteins
Federico Pietrocola,Guillermo Mariño,Delphine Lissa,Erika Vacchelli,Shoaib Ahmad Malik,Mireia Niso-Santano,Naoufal Zamzami,Lorenzo Galluzzi,Maria Chiara Maiuri,Guido Kroemer +9 more
TL;DR: A robust negative correlation could be established between autophagy induction and the acetylation levels of cytoplasmic proteins, as determined by a novel immunofluorescence staining protocol that allows for the exclusion of nuclear components from the analysis.
Journal ArticleDOI
Functions of BCL-XL at the Interface between Cell Death and Metabolism
Judith Michels,Oliver Kepp,Laura Senovilla,Delphine Lissa,Maria Castedo,Guido Kroemer,Lorenzo Galluzzi +6 more
TL;DR: The functions of BCL-XL at the interface between cell death and metabolism are discussed, which appear to play a prominent role in the regulation of multiple distinct types of cell death, including apoptosis and regulated necrosis.
Journal ArticleDOI
Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention
Delphine Lissa,Laura Senovilla,Laura Senovilla,Santiago Rello-Varona,Santiago Rello-Varona,Santiago Rello-Varona,Ilio Vitale,Mickaël Michaud,Mickaël Michaud,Mickaël Michaud,Federico Pietrocola,Federico Pietrocola,Federico Pietrocola,Alice Boilève,Alice Boilève,Alice Boilève,Florine Obrist,Florine Obrist,Florine Obrist,Chloé Bordenave,Chloé Bordenave,Chloé Bordenave,Pauline Garcia,Pauline Garcia,Pauline Garcia,Judith Michels,Judith Michels,Judith Michels,Mohamed Jemaà,Mohamed Jemaà,Mohamed Jemaà,Oliver Kepp,Maria Castedo,Guido Kroemer +33 more
TL;DR: The results suggest that the chemopreventive action of resveratrol and aspirin involves the elimination of tetraploid cancer cell precursors.