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Dennis H. Bamford

Researcher at University of Helsinki

Publications -  375
Citations -  19352

Dennis H. Bamford is an academic researcher from University of Helsinki. The author has contributed to research in topics: RNA & Bacteriophage. The author has an hindex of 72, co-authored 374 publications receiving 18266 citations. Previous affiliations of Dennis H. Bamford include Max Planck Society & Delft University of Technology.

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A Mechanism for Initiating RNA-Dependent RNA Polymerization

TL;DR: The results provide a working model for the initiation of replication and transcription of double-stranded RNA viruses and flaviviruses and suggest a mechanism by which the incoming double-Stranded RNA is opened up to feed the template through to the active site, while the substrates enter by another route.
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What does structure tell us about virus evolution

TL;DR: Structural analyses of virion architecture and coat protein topology have revealed unexpected similarities, not visible in sequence comparisons, suggesting a common origin for viruses that infect hosts residing in different domains of life (bacteria, archaea and eukarya).
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Viral Evolution Revealed by Bacteriophage PRD1 and Human Adenovirus Coat Protein Structures

TL;DR: Although these two dsDNA viruses infect hosts from very different kingdoms, their striking similarities, from major coat protein through capsid architecture, strongly suggest their evolutionary relationship.
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qiRNA is a new type of small interfering RNA induced by DNA damage

TL;DR: The results suggest that QDE-1 is the DNA-dependent RNA polymerase that produces aRNAs, and the Neurospora RNA interference mutants show increased sensitivity to DNA damage, suggesting a role for qiRNAs in theDNA-damage response by inhibiting protein translation.