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Dhananjay Jere

Researcher at Seoul National University

Publications -  37
Citations -  1512

Dhananjay Jere is an academic researcher from Seoul National University. The author has contributed to research in topics: Gene delivery & Polyethylenimine. The author has an hindex of 15, co-authored 35 publications receiving 1388 citations. Previous affiliations of Dhananjay Jere include Hoffmann-La Roche.

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Chemical modification of chitosan as a gene carrier in vitro and in vivo

TL;DR: The role of chitosan as a carrier of controlled release of DNA and small interfering RNA is described and the role of several factors for the enhancement of transfection efficiency and cell specificity in vitro are summarized.
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The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway.

TL;DR: Development of a new polymeric gene carrier for cancer cell-targeting, designed to enhance the intracellular delivery of shRNA and reduce cytotoxicity, and results suggest that FC-g-PEI may be useful for shRNA-based gene therapy are reported.
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Degradable polyethylenimines as DNA and small interfering RNA carriers.

TL;DR: This review paper summarizes and discusses the recent advances with degradable PEIs, such as cross-linked and grafted PEIs for DNA and siRNA delivery, and enhances transfection of DNA or small interfering RNA for efficient gene expression or silencing.